Infect Chemother.  2004 Apr;36(2):122-126.

A Case of Multiple Intracerebral Aspergillus Abscess in Neonate

Affiliations
  • 1Department of Neurosurgery, Presbyterian Medical Center, Jeonju, Korea.
  • 2Department of Neurosurgery, Reseach Institute for Clinical Medicine, Chonbuk National University Medical School/Hospital, Jeonju, Korea. jp-eun@hanmail.net

Abstract

Fungal infection of the central nervous system tends to occur in immunosuppressed patients. In the pediatric population, it is usually seen in severely immunocompromised patients, particulary in children with chronic granulomatous disease, hematopoietic malignancies, and those receiving chemotherapy or corticosteroid therapy. Literature indicates rare survivors from neonatal aspergillosis. We report a case of multiple brain abscess caused by Aspergillus in a 15-day-old male neonate, who had suffered from high fever, generalized seizure, severe dehydration, and azotemia. The patient was immunologically competent and successfully treated with surgical removal and antifungal agents.

Keyword

Brain Abscess; Aspergillus; Neonate; Surgical removal; Antifungal agents

MeSH Terms

Abscess*
Antifungal Agents
Aspergillosis
Aspergillus*
Azotemia
Brain Abscess
Central Nervous System
Child
Dehydration
Drug Therapy
Fever
Granulomatous Disease, Chronic
Hematologic Neoplasms
Humans
Immunocompromised Host
Infant, Newborn*
Male
Seizures
Survivors
Antifungal Agents
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