Korean J Gastroenterol.
2014 Sep;64(3):148-153. 10.4166/kjg.2014.64.3.148.
Current Issues on the Treatment of Chronic Constipation
- Affiliations
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- 1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
- 2Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
- 3Institute for Digestive Research, Soonchunhyang University College of Medicine, Seoul, Korea.
- 4Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
- 5Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea.
- 6Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea.
- 7Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea.
- 8Department of Internal Medicine and Institute for Medical Science, Keimyung University School of Medicine, Daegu, Korea.
- 9Department of Internal Medicine, Wonkwang University School of Medicine, Iksan, Korea. medcsc@wmc.wonkwang.ac.kr
- KMID: 2160656
- DOI: http://doi.org/10.4166/kjg.2014.64.3.148
Abstract
- Chronic constipation is a very common clinical problem with its prevalence of up to 14% in the general population. It is not a life-threatening disease, but since patient's satisfaction to the treatment is known to be as low as 50%, chronic constipation still remains a clinically challenging problem. Fortunately, many new treatments have been introduced or are to be introduced in the near future. This article will review the basic concepts and the results of recent studies on the new treatments for chronic constipation.
Keyword
MeSH Terms
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Chloride Channel Agonists/therapeutic use
Chronic Disease
Constipation/*drug therapy/epidemiology
Humans
Laxatives/*therapeutic use
Polyethylene Glycols/therapeutic use
Prevalence
Probiotics/therapeutic use
Serotonin 5-HT4 Receptor Agonists/therapeutic use
Chloride Channel Agonists
Laxatives
Serotonin 5-HT4 Receptor Agonists
Polyethylene Glycols
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