Ann Dermatol.  2011 Oct;23(Suppl 2):S264-S266. 10.5021/ad.2011.23.S2.S264.

Cutaneous Schwannoma Presented as a Pedunculated Protruding Mass

Affiliations
  • 1Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea. oddung93@yuhs.ac

Abstract

Schwannoma is a benign neoplasm of the nerve sheath origin. It arises from the nerve sheath of large peripheral or cranial nerves and occurs at the level of the subcutaneous fat layer or deeper layer. Cutaneous schwannoma occurs more superficially and usually presents as a solitary dermal or subcutaneous nodule. We describe a case of cutaneous schwannoma that presented as an erythematous pedunculated protruding mass on the left flank of a 19-year-old female. It was clinically diagnosed as a granuloma pyogenicum. Shaving biopsy was conducted and histological examination revealed an encapsulated tumor mass containing dense, spindle-shaped cells whose nuclei are arranged back to back representing Verocay body, and a diagnosis of schwannoma was made. This is an unusual case of cutaneous schwannoma that presented as a pedunculated protruding mass.

Keyword

Cutaneous; Protruding; Schwannoma

MeSH Terms

Biopsy
Cranial Nerves
Female
Granuloma, Pyogenic
Humans
Neurilemmoma
Subcutaneous Fat
Young Adult

Figure

  • Fig. 1 Tumor presented as a pink protruding mass with a slender stalk on the patient's left flank.

  • Fig. 2 (A) Discrete encapsulated dermal tumor in the upper dermis was completely removed through the shaving biopsy (H&E, original magnification, ×40). (B) Tumor was composed of mostly Antoni A patterns with some Antoni B patterns and dilated vessels (H&E, ×100).

  • Fig. 3 (A) Tumor cells were arranged in an orderly fashion, forming palisades and Verocay bodies. (B) Part of the tumor mass consisted of scattered spindle cells in loose and myxoid stroma (H&E, ×400). Tumor cells showed positivity for S100 (C) and negativity for neurofilaments (D) (×400).


Cited by  1 articles

Schwannoma Presenting as a Scalp Mass: A Case Report with Magnetic Resonance Imaging Findings
Jong Seo Park, Jungyoon Moon, Soo Ick Cho, Je-Ho Mun
Ann Dermatol. 2020;32(1):64-68.    doi: 10.5021/ad.2020.32.1.64.


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