J Korean Soc Pediatr Nephrol.
2001 Oct;5(2):206-209.
A Case of C1q Nephropathy in Steroid-Dependent Nephrotic Syndrome
- Affiliations
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- 1Department of Pediatrics, Ewha Womans University, College of Medicine, Ewha Medical Research Center Seoul, Korea. sjoolee@mm.ewha.ac.kr
- 2Department of Pathology, Ewha Womans University, College of Medicine, Ewha Medical Research Center Seoul, Korea.
Abstract
- C1q nephropathy is an immune complex glomerulonephritis defined by the presence of mesangial C1q deposits in immunofluorescence microscopy and electron dense deposits on electron microscopy. It was described as a distinct disease entity in 1985 by Jennette and Hipp. Thirty four cases were reported in the literature but there has been no pediatric case reported in Korea yet. It commonly presents with steroid-resistent nephrotic syndrome in older children and young adults, and occasionally nephritic-nephrotic syndrome or rapidly progressive glomerulonephritis. We report a case of C1q nephropathy in a 23-month-old girl with steroid-dependent nephrotic syndrome.
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