Korean J Hematol.
1997 Aug;32(2):312-317.
A Case of Treatment of Serum EB Virus Antibody Positive Patient Presented with Evans Syndrome
- Affiliations
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- 1Department of Internal Medcine, Holy Family Hospital, Catholic University Medical College, Seoul, Korea.
- 2Cancer Center, Albert-Einstein University, NewYork, USA.
Abstract
- Evans syndrome is defined as the simultaneous or sequential occurrence of Coombs- positive hemolytic anemia and idiopathic thrombocytopenia. The clinical course is characterized by periods of remission and exacerbation with variable, and often disappointing responses to therapy. We experienced a case of serum Epstein-Barr virus antibody positive patient presented with Evans syndrome in a 31-year-old woman whose chief complaints were dyspnea and general weakness and whose disease responded to the multimodality therapy including prednisolone, plasmapheresis, intravenous immunoglobulin (IVIG), and alternate-day cyclosporine A and prednisolone. This is the encouraging report of the use of multimodality treatment with prednisolone, plasmapheresis, IVIG, and cyclosporine A and prednisolone in a serum EV virus antibody positive patient presented with Evans syndrome.
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