Korean J Occup Environ Med.  1995 Feb;7(1):186-190.

A Suspicious Case of Dimethylformamide Induced Fulminant Hepatitis in Synthetic Leather Workers

Affiliations
  • 1Department of Preventive medicine, College of Medicine, Han Yang University, Korea.
  • 2Center for Occupational Health, Hanyang University Hospital, Korea.
  • 3Institute for Industrial Health, Korean Industrial Health Association, Korea.

Abstract

A man who worked in the synthetic leather manufacturing plant for 3 months died at November 3. Author review the medical record, the death certificate, and interviewed his wife and the doctor who treated him. His major job was DMF handling. At the working place, he felt severe health problem, and admitted to the hospital via emergency clinic. He complained severe abdominal pain and showed jaundice and ascites, He suffered hepatic coma and respiratory insufficiency from fulminant hepatitis from 19th days after admission. Drug abuse, hepatitis (A, B, C), and alcoholic hepatitis were rule out with his history and serological study data, As a result, author couldn't find any cause of death, but fuIminant hepatitis from DMF toxicity.

Keyword

Toxic hapatitis; Dimethylformamide

MeSH Terms

Abdominal Pain
Ascites
Cause of Death
Death Certificates
Dimethylformamide*
Emergencies
Hepatic Encephalopathy
Hepatitis*
Hepatitis, Alcoholic
Humans
Jaundice
Medical Records
Plants
Respiratory Insufficiency
Spouses
Substance-Related Disorders
Dimethylformamide
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