Clinical characteristics of the associated histopathological findings in benign prostatic hyperplasia

Lee, Sang Yang; Park, Young Yo

Abstract

We studied on the correlation between the associated histopathological lesions in benign prostatic hyperplasia and the clinical findings in 283 patients. The patients were divided into 5 groups according to the Following associated histopathological lesions : Nonspecific inflammation (274 patients. 96.8%). Granulomatous inflammation (7 patients. 2.4%. including tuberculosis 2 patients). infarction (8 patients, 2.8%). dysplasia (10 patients, 3.5%) and occult cancer (9 patients. 3.2%). There was no significant difference among the groups in age. The duration of symptoms was shorter in the infarction and occult cancer group than the others. The degree of inflammatory lesions were not correlated with preoperative urinalysis findings. Irritative symptom score was high in the patient of severe inflammatory lesion (P<0.05). Acute urinary retention was more common in the infarction group (62.5%) than the non-infarction group (10.9%). Prostatic; dysplasia was more common and higher degree in the occult cancer group (33.3%) than no cancer group(2.5%). So more precise pathological examination are necessary when dysplasia. especially severe dyplasia, is present. In conclusion. most patients of the benign prostatic hyperplasia had some associated histopathologic abnormal lesions, so more careful histopathological examination is needed to understand the progression of the disease.