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Safety of laparoscopic appendectomy for the management of acute appendicitis during pregnancy

Park YY

Laparoscopic appendectomy during pregnancy is widely accepted as a safe procedure in Korea, where the rate of laparoscopic surgery is high. Although the Society of American Gastrointestinal and Endoscopic Surgeons...
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Predictive factors for conservative treatment failure of right colonic diverticulitis

Park YY, Nam S, Han JH, Lee J, Cheong C

Purpose: Conservative treatment is the first-line therapy for acute colonic diverticulitis without severe complications, but treatment failure may increase hospitalization duration, medical costs, and morbidities. Usage of the modified Hinchey...
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Step-wise learning of laparoscopic low anterior resection

Park YY, Lee KY

A primary goal of training is the development of one’s own procedure by self-learning, which can be facilitated by laparoscopic surgery owing to its recordable system. This video demonstrates laparoscopic...
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Analysis on the Effects of Particular Matter Distribution on the Number of Outpatient Visits for Allergic Rhinitis

Park JH, Park YY, Lee E, Lee KS

Background: This study aims to analyze the effects of air pollutants, such as particular matter, to the number of outpatient visits for allergic rhinitis in eup, myeon, and dong administrative...
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A Study on the Regional Factors Affecting the Death Rates of Cardio-Cerebrovascular Disease Using the Spatial Analysis

Park YY, Park JH, Park YH, Lee KS

Background: The purpose of this study was to analyze the relationship between the regional characteristics and the age-adjusted cardio-cerebrovascular disease mortality rates (SCDMR) in 229 si·gun·gu administrative regions. Methods: SCDMR of...
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Involvement of the TNF-α Pathway in TKI Resistance and Suggestion of TNFR1 as a Predictive Biomarker for TKI Responsiveness in Clear Cell Renal Cell Carcinoma

Hwang HS, Park YY, Shin SJ, Go H, Park JM, Yoon SY, Lee JL, Cho YM

BACKGROUND: Mechanism and predictive biomarkers for tyrosine kinase inhibitor (TKI) resistance of advanced clear cell renal cell carcinoma (ccRCC) have not been fully evaluated. METHODS: We performed gene expression profiling on...
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Surgical Treatment of Rectal Prolapse: A 10-Year Experience at a Single Institution

Nacion AJ, Park YY, Kim HS, Yang SY, Kim NK

PURPOSE: Despite the plethora of surgical options, there is no consensus regarding the best treatment for rectal prolapse. This study is aimed at evaluating our experience with its treatment and...
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Impact of Adjuvant Chemotherapy Completion on Oncologic Outcomes in ypTNMstage 2 Rectal Cancer Patients

Park YY, Lee KY, Kim NK, Lee SB, Kim GR, Min BS, Oh ST

PURPOSE: Adjuvant chemotherapy (aCT) in rectal cancer patients who have undergone curative resection after neoadjuvant chemoradiation (nCRT) is controversial. We aimed to investigate the benefits of using aCT and the...
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Short-term Outcomes After Upfront Chemotherapy Followed by Curative Surgery in Metastatic Colon Cancer: A Comparison With Upfront Surgery Patients

Han MH, Park YY, Pratap S, Han YD, Cho MS, Hur H, Min BS, Lee KY, Kim NK

PURPOSE: Upfront systemic chemotherapy with target agents has been recommended for patients with stage IV colon cancer. Some with partial response are considered for curative resection. There is high risk...
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Branchial cleft cyst in the parotid gland in a human immunodeficiency virus-negative patient

Park YY, Yoon JS, Bang SS, Ahn HC

In branchial lymphoepithelial cyst (BLEC), which is also known as branchial cleft cyst, the remnants of a branchial arch develop into a cyst, causing swelling. The first case of BLEC...
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A Case of Newly Found Lymphoepithelial Carcinoma in Retropharynx of the Patient Who Had Been in the NED State of Nasopharyngeal Carcinoma: Controversy about the Recurrence of Undiffentiated Nasopharyngeal Carcinoma

Park YY, Lee EJ, Cho JG, Woo JS

Lymphoepithelial carcinoma is a rare subtype of head and neck malignancy. Histologically, it is an undifferentiated carcinoma accompanied by a prominent reactive lymphoplasmacytic infiltrate. We report a case of anewly...
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Flap selection for reconstruction of wide palatal defect after cancer surgery

Park YY, Ahn HC, Lee JH, Chang JW

BACKGROUND: The resection of head and neck cancer can result in postoperative defect. Many patients have difficulty swallowing and masticating, and some have difficulty speaking. Various types of flaps are...
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Anti-inflammatory Role of Mesenchymal Stem Cells in an Acute Lung Injury Mouse Model

Huh JW, Kim WY, Park YY, Lim CM, Koh Y, Kim MJ, Hong SB

BACKGROUND: Mesenchymal stem cells (MSCs) attenuate injury in various lung injury models through paracrine effects. We hypothesized that intratracheal transplantation of allogenic MSCs could attenuate lipopolysaccharide (LPS)-induced acute lung injury...
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Critical and Challenging Issues in the Surgical Management of Low-Lying Rectal Cancer

Nacion AJ, Park YY, Yang SY, Kim NK

Despite innovative advancements, the management of distally located rectal cancer (RC) remains a formidable endeavor. The critical location of the tumor predisposes it to a circumferential resection margin that tends...
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Rab25 augments cancer cell invasiveness through a β1 integrin/EGFR/VEGF-A/Snail signaling axis and expression of fascin

Jeong BY, Cho KH, Jeong KJ, Park YY, Kim JM, Rha SY, Park CG, Mills GB, Cheong JH, Lee HY

The small GTP-binding protein Rab25 is associated with tumor formation and progression. However, recent studies have shown discordant effects of Rab25 on cancer cell progression depending on cell lineage. In...
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Perianal Paget disease: a report of 2 cases

Park YY, Kim M, Cheong C, Kim SK, Song SY, Chung KY, Kim NK

Extramammary Paget disease (EMPD) is a rare cutaneous neoplasm. Perianal Paget disease (PPD) is a subset of EMPD manifesting perianal lesions. Two cases of PPD in Severance Hospital are described...
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Clinical Characteristics of Benign Oral Cavity Tumors: A Single-Institution Retrospective Study of 257 Patients

Kim SJ, Park YY, Im H, Kim TH, Bang SH, Cho JG, Woo JS

BACKGROUND AND OBJECTIVES: The study aimed to analyze the histopathologic types and clinical characteristics of benign oral cavity tumors and to identify their possible etiologic factors. SUBJECTS AND METHOD: This was...
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The Impact of Thyroid Nodule Size and Fine-Needle Aspiration Biopsy Result on the Risk of Malignancy in the Patients Who Underwent Thyroidectomy

Im H, Park YY, Cho JG, Baek SK, Kwon SY, Jung KY, Woo JS

BACKGROUND AND OBJECTIVES: The frequency of ultrasonography and cytological examinations for thyroid nodules has increased. But the efficacy of fine needle aspiration biopsy varies according to the size of the...
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The p90 ribosomal S6 kinase 2 specifically affects mitotic progression by regulating the basal level, distribution and stability of mitotic spindles

Park YY, Nam HJ, Do M, Lee JH

RSK2, also known as RPS6KA3 (ribosomal protein S6 kinase, 90 kDa, polypeptide 3), is a downstream kinase of the mitogen-activated protein kinase (MAPK) pathway, which is important in regulating survival, transcription,...
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Associations between Single Nucleotide Polymorphisms of High Mobility Group Box 1 Protein and Clinical Outcomes in Korean Sepsis Patients

Lee K, Chang Y, Song K, Park YY, Huh JW, Hong SB, Lim CM, Koh Y

PURPOSE: High mobility group box 1 (HMGB1) plays a central role in the pathogenesis of sepsis and multiple organ dysfunction syndromes. We investigated the associations of a single nucleotide polymorphism...
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