J Korean Assoc Maxillofac Plast Reconstr Surg.  2009 May;31(3):249-253.

Use of corticosteroids in the treatment of localized langerhans cell histiocytosis of the mandible : Case report

• Choi JY
• Lee SH
• Yoon HJ

Abstract

Langerhans cell histiocytosis(LCH), previously known as histiocytosis X, is rare, proliferative disorder in which the accumulation of pathologic Langerhans cell leads to tissue infiltration and destruction. The jaw is involved 10~20% of all LCH and most common oral symptoms are jaw swelling or a palpation mass. Most of subjects are males and disease appears to start before the age of 10 years. An 11 years old girl was referred from pediatric department. Histological examination confirmed the diagnosis LCH. She was treated intra-lesional injection of corticosteroid. The overall outcome was excellent. After a follow-up period of 20 month, the patient present with no evidence of residual disease on Panoramic view and whole body bone scan. We report this early recognized LCH case treated by corticoid injection in good progress with literature review

Keyword

Langerhans cell histiocytosis; Eosinophilic granuloma; Corticosteroids; Intralesional injection

MeSH Terms

Adrenal Cortex Hormones
Eosinophilic Granuloma
Follow-Up Studies
Histiocytosis, Langerhans-Cell
Humans
Injections, Intralesional
Jaw
Male
Mandible
Palpation
Adrenal Cortex Hormones