J Korean Assoc Oral Maxillofac Surg.  2019 Jun;45(3):167-172. 10.5125/jkaoms.2019.45.3.167.

Langerhans cell histiocytosis of the mandible: two case reports and literature review

• Hwang DS
• Lee JS
• Kim UK
• Park HR
• Ryu MH
• Lee JH
• Jung YH
• Kim GC

• KMID: 2451324
• DOI: http://doi.org/10.5125/jkaoms.2019.45.3.167

Abstract

Langerhans cell histiocytosis (LCH) is a rare disorder characterized by the proliferation of dendritic cells resulting in local or systemic symptoms. The clinical symptoms of patients with Langerhans cell histiocytosis depend on the site and the degree of involvement. This article describes two case histories of unifocal bony Langerhans cell histiocytosis with mandibular involvement and further discusses the appropriate management of such via a review of the literature.

Keyword

Langerhans cell histiocytosis; Unifocal Langerhans cell histiocytosis

MeSH Terms

Dendritic Cells
Histiocytosis, Langerhans-Cell*
Humans
Mandible*