Korean J Dermatol.  2015 Dec;53(10):802-805.

A Case of Pemphigoid Gestationis with Involvement of the Face

Affiliations
  • 1Department of Dermatology, Busan Paik Hospital, College of Medicine, Inje University, Busan, Korea. derma09@hanmail.net

Abstract

Pemphigoid gestationis, also known as herpes gestationis, is a rare blistering disease associated with pregnancy, caused by autoantibody to the basement membrane component. It occurs in the second or third trimester of pregnancy or directly after delivery, as erythematous, urticarial papules, and plaques on the whole body, which aggravate to vesicles and bullae with severe pruritus. Histopathologically, subepidermal blisters and eosinophilic spongiosis are shown, and linear deposition of C3 in the dermoepidermal junction is seen on direct immunofluorescence assay. We present the case of 35-year-old woman who was diagnosed with pemphigoid gestationis, with the involvement of the uncommon site of the face.

Keyword

Herpes gestationis; Pemphigoid gestationis

MeSH Terms

Adult
Basement Membrane
Blister
Eosinophils
Female
Fluorescent Antibody Technique, Direct
Humans
Pemphigoid Gestationis*
Pemphigoid, Bullous*
Pregnancy
Pregnancy Trimester, Third
Pruritus
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