- Exploratory Study of Epidermis, Basement Membrane Zone, Upper Dermis Alterations and Wnt Pathway Activation in Melasma Compared to Adjacent and Retroauricular Skin
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Espósito , Brianezi G, de Souza N, Miot LD, Miot HA
- KMID: 2471335
- Ann Dermatol.
- 2020 Apr;32(2):101-108.
- doi: 10.5021/ad.2020.32.2.101
BACKGROUND: Melasma is a chronic acquired focal hypermelanosis which pathogenesis has not been fully elucidated. Classical pathophysiologic studies have analysed the affected and perilesional areas, but little is known about... -
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- Clinical Analysis of Findings for Anterior Segment Optical Coherent Tomography in Recurrent Corneal Erosion Syndrome
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Kim YM, Eom HD, Yoon DH, Kim HK
- KMID: 2466165
- J Korean Ophthalmol Soc.
- 2019 Dec;60(12):1155-1161.
- doi: 10.3341/jkos.2019.60.12.1155
PURPOSE: To evaluate the correlation between abnormal findings seen in anterior segment optical coherent tomography and the recurrence rate in patients with recurrent corneal erosion syndrome. METHODS: Between January 2015 and... -
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- Concurrent Anti-glomerular Basement Membrane Nephritis and IgA Nephropathy
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Suh KS, Choi SY, Bae GE, Choi DE, Yeo MK
- KMID: 2465440
- J Pathol Transl Med.
- 2019 Nov;53(6):399-402.
- doi: 10.4132/jptm.2019.08.05
Anti–glomerular basement membrane (GBM) nephritis is characterized by circulating anti-GBM antibodies and crescentic glomerulonephritis (GN) with deposition of IgG along the GBM. In a limited number of cases, glomerular immune... -
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- Pathology of C3 Glomerulopathy
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Shin SJ, Seong Y, Lim BJ
- KMID: 2464933
- Child Kidney Dis.
- 2019 Oct;23(2):93-99.
- doi: 10.3339/jkspn.2019.23.2.93
C3 glomerulopathy is a renal disorder involving dysregulation of alternative pathway complement activation. In most instances, a membranoproliferative pattern of glomerular injury with a prevalence of C3 deposition is observed... -
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- Genetic Basis of Steroid Resistant Nephrotic Syndrome
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Park E
- KMID: 2464932
- Child Kidney Dis.
- 2019 Oct;23(2):86-92.
- doi: 10.3339/jkspn.2019.23.2.86
Steroid-resistant nephrotic syndrome (SRNS) has long been a challenge for clinicians due to its poor responsiveness to immunosuppressants, and rapid progression to end-stage renal disease. Identifying a monogenic cause for... -
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- Genes and Pathways Regulating Decline in Lung Function and Airway Remodeling in Asthma
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Hur GY, Broide DH
- KMID: 2452752
- Allergy Asthma Immunol Res.
- 2019 Sep;11(5):604-621.
- doi: 10.4168/aair.2019.11.5.604
Asthma is a common disorder of the airways characterized by airway inflammation and by decline in lung function and airway remodeling in a subset of asthmatics. Airway remodeling is characterized... -
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- De novo mutations in COL4A5 identified by whole exome sequencing in 2 girls with Alport syndrome in Korea
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Han KH, Park JE, Ki CS
- KMID: 2451970
- Korean J Pediatr.
- 2019 May;62(5):193-197.
- doi: 10.3345/kjp.2018.06772
Alport syndrome (ATS) is an inherited glomerular disease caused by mutations in one of the type IV collagen novel chains (α3, α4, and α5). ATS is characterized by persistent microscopic... -
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- The Effects of the 3-OH Group of Kaempferol on Interfollicular Epidermal Stem Cell Fate
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Chae JB, Choi HR, Shin JW, Na JI, Huh CH, Park KC
- KMID: 2428925
- Ann Dermatol.
- 2018 Dec;30(6):694-700.
- doi: 10.5021/ad.2018.30.6.694
BACKGROUND: Kaempferol (3,4′,5,7-tetrahydroxyflavone) is a flavonoid known to have a wide range of pharmacological activities. The 3-OH group in flavonoids has been reported to determine antioxidant activities. OBJECTIVE: We tested whether... -
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- Piperacillin-Tazobactam-Induced Linear IgA Bullous Dermatosis Supported by a T-Cell Activation Assay
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Ho YH, Chiu YW, Liu HN
- KMID: 2419750
- Ann Dermatol.
- 2018 Oct;30(5):588-591.
- doi: 10.5021/ad.2018.30.5.588
Linear immunoglobulin (Ig) A bullous dermatosis (LABD) is a rare subepidermal autoimmune blistering disease characterized by linear IgA deposits at the basement membrane zone visualized with direct immunofluorescence (DIF). Most... -
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- Basement Membrane Status Is Intact in Urticarial Dermatitis vs. Adult-Onset Atopic Dermatitis
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Kim TI, Park HJ, Won YY, Choi H, Jeong KH, Sung JY, Shin MK
- KMID: 2414701
- Ann Dermatol.
- 2018 Apr;30(2):258-261.
- doi: 10.5021/ad.2018.30.2.258
No abstract available. -
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- Ameliorative effect of vitamin B12 on seminiferous epithelium of cimetidine-treated rats: a histopathological, immunohistochemical and ultrastructural study
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Elsaed WM, Bedeer RF, Eladl MA
- KMID: 2418395
- Anat Cell Biol.
- 2018 Mar;51(1):52-61.
- doi: 10.5115/acb.2018.51.1.52
Cimetidine is an H2 receptor antagonist that has an antiandrogenic effect. It intervenes with the conversion of testosterone into estrogen in the Sertoli cells with accompanying testicular structural changes. In... -
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- Long-term Prognosis of thin Glomerular Basement Membrane Nephropathy in Children: A Retrospective Single Center Study
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Lim MH, Bae HJ, Jang KM, Park YH
- KMID: 2394438
- Child Kidney Dis.
- 2017 Oct;21(2):41-46.
- doi: 10.3339/jkspn.2017.21.2.41
PURPOSE: Thin glomerular basement membrane nephropathy (TBMN) is, along with the IgA nephropathy, the most common cause of asymptomatic hematuria in Korean children. TBMN is usually a benign renal disease... -
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- Unusual Case of Posterior Reversible Encephalopathy Syndrome in a Patient with Anti-glomerular Basement Membrane Antibody Glomerulonephritis: A Case Report and Review of the Literature
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Cha B, Kim DY, Jang H, Hwang SD, Choi HJ, Kim MJ
- KMID: 2391007
- Electrolyte Blood Press.
- 2017 Sep;15(1):12-16.
- doi: 10.5049/EBP.2017.15.1.12
Posterior reversible encephalopathy syndrome (PRES) is characterized by a clinical and radiological entity with the sudden onset of seizures, headache, altered consciousness, and visual disturbances in patients with the findings... -
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- Systemic Lupus Erythematosus Presenting as Stevens-Johnson Syndrome: A Case Report
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Lee KG, Koh BY, Kwon ES, Myung KB, Kwon MH, Cheong SH
- KMID: 2386240
- Korean J Dermatol.
- 2017 Jun;55(5):293-296.
Acute cutaneous lupus erythematosus (ACLE) on the face is a usual pattern of presentation. However, it can rarely present with a generalized distribution. A hyperacute form of ACLE can mimic... -
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- Recent Research Trend for Ménière's Disease
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Nam SI
- KMID: 2385913
- Res Vestib Sci.
- 2017 Jun;16(2):39-46.
- doi: 10.21790/rvs.2017.16.2.39
Ménière's disease is a poorly understood disorder of the inner ear characterized by intermittent episodic vertigo, fluctuating hearing loss, ear fullness and tinnitus. In this paper, we present a review... -
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- Transcriptional regulatory networks underlying the reprogramming of spermatogonial stem cells to multipotent stem cells
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Jeong HS, Bhin J, Kim HJ, Hwang D, Lee DR, Kim KS
- KMID: 2382706
- Exp Mol Med.
- 2017 Apr;49(4):e315.
- doi: 10.1038/emm.2017.2
Spermatogonial stem cells (SSCs) are germline stem cells located along the basement membrane of seminiferous tubules in testes. Recently, SSCs were shown to be reprogrammed into multipotent SSCs (mSSCs). However,... -
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- A case of generalized argyria presenting with muscle weakness
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Jung I, Joo EJ, Suh BS, Ham CB, Han JM, Kim YG, Yeom JS, Choi JY, Park JH
- KMID: 2455023
- Ann Occup Environ Med.
- 2017 ;29(1):45.
- doi: 10.1186/s40557-017-0201-0
BACKGROUND: Argyria is a rare irreversible cutaneous pigmentation disorder caused by prolonged exposure to silver. Herein, we report a case of generalized argyria that developed after chronic ingestion of soluble... -
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- Transplantation of Autologous Bone Marrow Mesenchymal Stem Cells into the Testes of Infertile Male Rats and New Germ Cell Formation
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Ghasemzadeh-Hasankolaei M, Batavani R, Eslaminejad MB, Sayahpour
- KMID: 2362519
- Int J Stem Cells.
- 2016 Nov;9(2):250-263.
- doi: 10.15283/ijsc16010
BACKGROUND: Mesenchymal stem cells (MSCs), have been suggested as a potential choice for treatment of male infertility. Yet, the effects of MSCs on regeneration of germinal epithelium of seminiferous tubules... -
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- Clinical Manifestations of Extruded Conjunctival Melanocytic Mass
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Jang SG, Park BG, Park YM, Lee JS
- KMID: 2357723
- J Korean Ophthalmol Soc.
- 2016 Nov;57(11):1691-1698.
- doi: 10.3341/jkos.2016.57.11.1691
PURPOSE: To investigate the clinical manifestations and characteristics of extruded conjunctival melanocytic mass. METHODS: A total of 33 patients who had extruded conjunctival melanocytic mass and who underwent excisional biopsy were... -
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- Renoprotective Effect of Gemigliptin, a Dipeptidyl Peptidase-4 Inhibitor, in Streptozotocin-Induced Type 1 Diabetic Mice
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Jung GS, Jeon JH, Choe MS, Kim SW, Lee IK, Kim MK, Park KG
- KMID: 2308629
- Diabetes Metab J.
- 2016 Jun;40(3):211-221.
- doi: 10.4093/dmj.2016.40.3.211
BACKGROUND: Dipeptidyl peptidase-4 (DPP-4) inhibitors are widely used in the treatment of patients with type 2 diabetes and have proven protective effects on diabetic kidney disease (DKD). Whether DPP-4 inhibitors... -
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