J Korean Ophthalmol Soc.  2008 Feb;49(2):293-302. 10.3341/jkos.2008.49.2.293.

Trabeculectomy with Mitomycin C versus Ahmed Valve Implantation in Pseudophakic Glaucomatous Eyes

• Lee TY
• Lee JH
• Cha SC

• KMID: 2127122
• DOI: http://doi.org/10.3341/jkos.2008.49.2.293

Abstract

PURPOSE: To compare the safety and efficacy of trabeculectomy using mitomycin C (MMC) with Ahmed valve implantation in pseudophakic glaucomatous eyes.
METHODS
We retrospectively reviewed the medical records of 68 pseudophakic glaucoma patients (68 eyes) who had undergone trabeculectomy with MMC (group T, 41 eyes) or Ahmed valve implantation (group A, 27 eyes). Intraocular pressure reduction rates, cumulative probabilities of surgical success, and postoperative complications were compared between two groups. Also, risk factors for surgical failures were analyzed.
RESULTS
Intraocular pressure levels at postoperative 12 months were significantly lower in group T (13.8+/-5.1 mmHg) than in group A (19.6+/-6.4 mmHg, p=0.001). Cumulative probabilities of surgical success at postoperative 12 months were significantly higher in group T (95.0%) than in group A (66.2%, p=0.000). No significant differences were noted in the occurrences of complications except hyphema in two groups. We found that a younger age (< or =50 years) and Ahmed valve implantation were significant risk factors for surgical failures.
CONCLUSIONS
Trabeculectomy with MMC can be more effective and preferable as a primary surgical option over Ahmed valve implantation for pseudophakic glaucomatous eyes.

Keyword

Ahmed valve; Pseudophakia; Trabeculectomy

MeSH Terms

Eye
Glaucoma
Humans
Hyphema
Intraocular Pressure
Medical Records
Mitomycin
Postoperative Complications
Pseudophakia
Retrospective Studies
Risk Factors
Trabeculectomy
Mitomycin

Figure

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  Figure 1. Mean intraocular pressure curve for trabeculectomy with mitomycin C (dashed line) and Ahmed valve implantation (solid line). Data are presented as mean±SEM.

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  Figure 2. Kaplan-Meier survival curve showing the cumulative probability of surgical success following trabeculectomy with mitomycin C and Ahmed valve implantation. There were greater probabilities of success in MMC trabeculectomy group than in Ahmed valve group (p=0.000, log rank test).

Reference

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