J Korean Ophthalmol Soc.  1993 Jan;34(1):26-34.

Clinical Analysis of Vogt- Koyanagi-Harada Disease

• Woo KI
• Chung H

Abstract

Clinical records of 41 patients with Vogt-Koyanagi-Harada disease (VKH disease) who had visited Seoul National University Hospital from 1986 to 1990 were reviewed. Twenty one patients were men and twenty patients were women. Extraocular manifestations included headache (64%), alopecia (34%), poliosis (24%), vitligo (12%), tinnitus (14%), and dysacousia (14%). Arden ratios in electro-oculogram (EOG) were low in the early stages of disease, and became improved with regaining vision. The amplitudes of electroretinogram (ERG), which were low in the early stage, recovered during medication in many cases. Visual prognosis was better if patients were treated with systemic steroid from the beginning. Factors contributing to recurrent or persistent inflammation despite of treatment included numerous extraocular manifestations and delayed treatment.

Keyword

Electroretinogram; Electro-oculogram; Visual acuity; Vogt-Koyanagi-Harada disease

MeSH Terms

Alopecia
Female
Headache
Humans
Inflammation
Male
Prognosis
Seoul
Tinnitus
Uveomeningoencephalitic Syndrome
Visual Acuity