J Korean Assoc Maxillofac Plast Reconstr Surg.  1997 Nov;19(4):383-394.

ORAL MICROBES ASSOCIATED WITH TITANIUM IMPLANT AND THEIR ANTIBIOTIC SUSCEPTIBILITY

• Kim SK
• Ryu SY

Abstract

This study was done to examine adherence of oral bacteria to titanium dental implant and to know the effective prophylactic antibiotics using an in vivo model. Three samples each of the implant material were set in an acrylic resin flange and placed in the maxillary buccal sulcus of twenty volunteers. At 6- and 54-hour intervals, each sample was placed on blood agar plate (BAP) and chocolate agar, and then they were incubated and identified. Also antibiotic susceptibility test was performed. The results obtained were as follows ; 1. The microorganims were chain-like Gram positive cocci and staphyline Gram positive cocci. Gram positive bacilli in order of frequency were found at 6-hour and 54-hour samples by Gram staining. 2. Streptococci was found predominantly at both 6-hour and 54-hour samples, but number of streptococci was decreased as compared to 6-hour samples. 3. There was no difference in the bacterial species adherent to implant between 6-hour and 54-hour samples. 4. All the microbes were sensitive to AMC(amoxacillin clavulanic acid), chloramphenicol, quinolone and vancomycin in the antibiotic susceptibility test. Above results suggest that streptococcus are mainly adhered to titanium implant after implant was placed in the oral cavity and AMC is the most recommendable antibiotics to prevent the peri-implant inflammation.

MeSH Terms

Agar
Anti-Bacterial Agents
Bacteria
Cacao
Chloramphenicol
Dental Implants
Gram-Positive Cocci
Inflammation
Mouth
Streptococcus
Titanium*
Vancomycin
Volunteers
Agar
Anti-Bacterial Agents
Chloramphenicol
Dental Implants
Titanium
Vancomycin