J Korean Soc Pediatr Nephrol.
2002 Apr;6(1):102-108.
Two cases of Hemolytic Uremic Syndrome Associated with Escherichia coli O114
- Affiliations
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- 1Department of Pediatrics, Asan Medical Center, University of Ulsan, College of Medicine, Korea. yspark@amc.seoul.kr
- 2Department of Clinical Pathology, Asan Medical Center, University of Ulsan, College of Medicine, Korea.
- 3Department of Clinical Pathology, Seoul National University College of Medicine, Korea.
Abstract
- We report two cases of hemolytic uremic syndrome (HUS) associated with Escherichia coli O114. Two cases were similar and showed the same clinical courses. After prodrome of diarrhea and vomiting lasting 1-2 days, azotemia persisted for about 10 days, and during that period, the patients were on peritoneal dialysis. They recovered without any sequelae after about 15 days. Direct multiplex PCR of stool culture revealed eae and stx2 gene and the result of ELISA done on the colony positive of eae gene confirmed Escherichia coli O114. This is the first report of HUS associated with Escherichia coli O114. We recommend, Shiga toxin producing bacterial infection must be considered and efforts should be made to scrutinize the organism in all diarrhea-prodrome HUS patients.
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