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Risk of Cause-Specific Mortality across Glucose Spectrum in Elderly People: A Nationwide Population-Based Cohort Study

Lee J, Kim HS, Song KH, Yoo SJ, Han K, Lee SH, Committee of Big Data, Korean Endocrine Society

Background: This study investigated the risk of cause-specific mortality according to glucose tolerance status in elderly South Koreans. Methods: A total of 1,292,264 individuals aged ≥65 years who received health examinations...
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Risk of Pancreatic Cancer and Use of Dipeptidyl Peptidase 4 Inhibitors in Patients with Type 2 Diabetes: A Propensity Score-Matching Analysis

Kim MK, Han K, Kwon HS, Yoo SJ

Background: The effects of dipeptidyl peptidase 4 (DPP-4) inhibitors over the course of long-term treatment remain unclear, and concerns have been raised regarding the role of DPP-4 inhibitors in carcinogenesis...
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Efficacy of Gemigliptin Add-on to Dapagliflozin and Metformin in Type 2 Diabetes Patients: A Randomized, Double-Blind, Placebo-Controlled Study (SOLUTION)

Lee BW, Min K, Hong EG, Ku BJ, Kang JG, Chon S, Lee WY, Park MK, Kim JH, Kim SY, Song K, Yoo SJ

Background: This study evaluated the efficacy and safety of add-on gemigliptin in patients with type 2 diabetes mellitus (T2DM) who had inadequate glycemic control with metformin and dapagliflozin. Methods: In this...
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Mortality and Severity of Coronavirus Disease 2019 in Patients with Long-Term Glucocorticoid Therapy: A Korean Nationwide Cohort Study

Ku EJ, Song K, Kim KM, Seo GH, Yoo SJ

Background: The severity of coronavirus disease 2019 (COVID-19) among patients with long-term glucocorticoid treatment (LTGT) has not been established. We aimed to evaluate the association between LTGT and COVID-19 prognosis. Methods:...
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Diagnosis of Scoliosis Using Chest Radiographs with a Semi-Supervised Generative Adversarial Network

Lee W, Shin K, Lee J, Yoo SJ, Yoon MA, Choi YW, Hong GS, Kim N, Paik S

Purpose To develop and validate a deep learning-based screening tool for the early diagnosis of scoliosis using chest radiographs with a semi-supervised generative adversarial network (GAN). Materials and Methods Using a semi-supervised learning...
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Long-term Outcomes of Vitrectomy with Internal Limiting Membrane Removal to Treat Macular Hole Retinal Detachment

Jeon YJ, Kim JW, Kim CG, Yoo SJ, Kim HS, Kim JY, Kim JH

Purpose: To evaluate the long-term clinical outcomes of vitrectomy with internal limiting membrane (ILM) removal for patients with macular hole retinal detachment (MHRD). Methods: We retrospectively reviewed the medical records of...
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Congenital Heart Surgery Skill Training Using Simulation Models: Not an Option but a Necessity

Yoo SJ, Hussein N, Barron DJ

Congenital heart surgery (CHS) is technically demanding, and its training is extremely complex and challenging. Training of the surgeon’s technical skills has relied on a preceptorship format in which the...
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Immediate Vitrectomy for Acute Endophthalmitis in Patients with a Visual Acuity of Hand Motion or Better

Kim J, Kim HS, Yoo SJ, Choi MJ, Lew Y, Kim JW, Cho HJ

Purpose: To determine the efficacy of immediate pars plana vitrectomy as the primary treatment for acute endophthalmitis in patients with a visual acuity (VA) of hand motion (HM) or better. Methods:...
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Isolated Tuberculous Myositis: A Systematic Review and Multicenter Cases

Kim JH, Lee JS, Choi BY, Cheon YH, Yoo SJ, Ju JH, Shin K, Kim ES, Baek HJ, Park W, Song YW, Hong WH, Lee YJ

Objective: To investigate the clinical features and associated underlying conditions of isolated tuberculous myositis (ITBM), a rare extrapulmonary tuberculosis (TB). Methods: A systematic literature search and a multicenter survey were performed...
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Low-Density Lipoprotein Cholesterol Level, Statin Use and Myocardial Infarction Risk in Young Adults

Jeong H, Han K, Yoo SJ, Kim MK

Objective: The consequences of blood lipid abnormalities for cardiovascular disease risk in young adults is unclear. Optimal lipid levels may also vary depending on whether a statin drug is taken....
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Identification of Stem Cell Related Gene Expression from the Osteosarcoma Cell Core Side

Lim C, Roh YH, Yoo SJ, Jeong DK, Nam KW

Osteosarcoma is the most frequent primary malignant bone tumor with higher incidences in children and adolescents. Despite clinical evolutions, patients with osteosacoma have had a poor prognosis. There has been...
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IDH1/2 mutations in acute myeloid leukemia

Byun JM, Yoo SJ, Kim HJ, Ahn JS, Koh Y, Jang JH, Yoon SS

The mutational and epigenetic landscape of acute myeloid leukemia (AML) has become increasingly well understood in recent years, informing on biological targets for precision medicine. Among the most notable findings...
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Biomechanical Comparative Study for Osteosynthesis of Pauwels Type III Femoral Neck Fractures: Conventional Devices versus Novel Fixed Angle Devices

Park DH, Seo YC, Kwon YU, Jung SH, Yoo SJ

Purpose: Osteosynthesis has been recommended for treatment of Pauwels type III femoral neck fractures in young patients. However, no implant of choice has been reported so far. This study was...
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Effects of N-acetylcystein on changes in parvalbumin-positive interneurons in the hippocampus after carbon monoxide poisoning

Kim ST, Yoo SJ

Purpose: The purpose of this study was to investigate effect of N-acetylcysteine (NAC) on the injury of putative parvalbumin positive interneurons defined by molecular marker and hippocampal long-term potentiation (LTP),...
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Gant Infrascapular Rheumatoid Nodules Mimicking Elastofibroma Dorsi: A Case Report

Hong HG, Yoo SJ, Choi YW, Paik SS, Jee SY, Kim YE

Rheumatoid nodules are the most common extra-articular presentations of rheumatoid arthritis. Although rheumatoid nodules can develop anywhere in the body, they develop most commonly in the subcutaneous region, where they...
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Long-Term Glycaemic Durability of Early Combination Therapy Strategy versus Metformin Monotherapy in Korean Patients with Newly Diagnosed Type 2 Diabetes Mellitus

Yoo SJ, Chang SA, Sohn TS, Kwon HS, Lee JM, Moon S, Proot P, Paldánius PM, Yoon KH

We assessed the glycaemic durability with early combination (EC; vildagliptin+metformin [MET], n=22) versus MET monotherapy (n=17), among newly-diagnosed type 2 diabetes mellitus (T2DM) enrolled (between 2012 and 2014) in the...
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Modeling of Changes in Creatine Kinase after HMG-CoA Reductase Inhibitor Prescription

Kim HS, Min J, Shinn J, Hong OK, Son JW, Lee SS, Kim SR, Yoo SJ

Background: Statin-associated muscle symptoms are one of the side effects that physicians should consider when prescribing statins. In this study, creatine kinase (CK) levels were measured following statin prescription, and...
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Metabolic Subtyping of Adrenal Tumors: Prospective Multi-Center Cohort Study in Korea

Ku EJ, Lee C, Shim J, Lee S, Kim KA, Kim SW, Rhee Y, Kim HJ, Lim JS, Chung CH, Chun SW, Yoo SJ, Ryu OH, Cho HC, Hong AR, Ahn CH, Kim JH, Choi MH

Background: Conventional diagnostic approaches for adrenal tumors require multi-step processes, including imaging studies and dynamic hormone tests. Therefore, this study aimed to discriminate adrenal tumors from a single blood sample...
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Seroprevalence and Risk Factors for Severe Fever with Thrombocytopenia Syndrome among the Korea National Park Service Workers

Kim DH, Kim KH, Yi J, Ko MK, Park SJ, Yoo SJ, Lee K, Park JH

Objectives: This study was carried out to understand the seroprevalence and risk factors for severe fever with thrombocytopenia syndrome (SFTS) among the Korea National Park Service (KNPS) workers. Methods: We used...
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Ultrasound-guided insertion of peripherally inserted central catheter after anesthetic induction in children undergoing surgery for moyamoya disease - Thirty cases report-

Ji SH, Yoo SJ, Cho SA, Jang YE, Kim EH, Lee JH, Kim JT, Kim HS

Background: Pediatric patients with moyamoya disease are vulnerable to ischemic attacks following physical or emotional stress, such as those experienced during blood sampling. A central venous catheter might be beneficial...
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