Korean J Gastrointest Endosc.  2002 Oct;25(4):213-216.

A Case of Hemolytic Uremic Syndrome Caused by Escherichia coli O8: Case Report

• Cho YH
• Park HJ
• Song KS
• Song YG
• Lee SI
• Park IS

Abstract

Since 1982, many countries have reported outbreaks or sporadic cases by enterohemorrhagic Escherichia coli (E. coli) serogroup strains, mainly E. coli O157 : H7. Hemorrhagic E. coli induces hemolytic uremic syndrome (HUS) in 10 to 15% of cases in infants and young chilidren. HUS is a clinical syndrome of hemolytic anemia, acute renal failure, and thrombocytopenia. We experienced a case of E. coli O8 as the causative organism of hemorrhagic colitis and hemolytic uremic syndrome in 16 year-old man. Hemorrhagic colitis was diagnosed by the sigmoidoscopy and E. coli O8 was identified in the stool culture. Hemolytic uremic syndrome was clinically diagnosed. A conservative management including total parenteral nutrition, plasma exchange transfusion, hemodialysis and continuous arteriovenous hemofiltration with dialysis resulted in a complete recovery of the patient. We herein report this manifestations of E. coli O8 and discuss the therapeutic issues related to hemorrhagic colitis and hemolytic uremic syndrome.

Keyword

Escherichia coli O8; Hemorrhagic colitis; Hemolytic uremic syndrome

MeSH Terms

Acute Kidney Injury
Adolescent
Anemia, Hemolytic
Colitis
Dialysis
Disease Outbreaks
Enterohemorrhagic Escherichia coli
Escherichia coli*
Escherichia*
Hemofiltration
Hemolytic-Uremic Syndrome*
Humans
Infant
Parenteral Nutrition, Total
Plasma Exchange
Renal Dialysis
Sigmoidoscopy
Thrombocytopenia