J Korean Ophthalmol Soc.  1995 Jan;36(1):120-124.

A Case of Chronic Progressive External Ophthalmoplegia

• Shin WK
• Choi BS
• Shin H

Abstract

Chronic progressive external ophthalmoplegia(CPEO) is rare syndrome, which is characterized by slowly progressive blepharoptosis, paralysis of extraocular muscle and has involvement of other organs, particularly the retina, heart, endocrine gland, and bony skeleton. Histological examination of muscle showes characteristic ragged red fibers. Electron microscopy reveals a number of abnormal mitochondria which contain paracrystalline inclusion bodies. We experienced a 50-year-old female with CPEO, that was pathologically proven by electron microscopy and bilateral levator levator advancements were given for ptosis.

Keyword

CPEO; Abnormal mitochondria; ptosis; ragged red fiber

MeSH Terms

Blepharoptosis
Endocrine Glands
Female
Heart
Humans
Inclusion Bodies
Microscopy, Electron
Middle Aged
Mitochondria
Ophthalmoplegia, Chronic Progressive External*
Paralysis
Retina
Skeleton