J Korean Med Sci.  1989 Jun;4(2):91-96. 10.3346/jkms.1989.4.2.91.

Chronic progressive external ophthalmoplegia (CPEO) with 'ragged red fibers': a case report

Affiliations
  • 1Department of Neurology, Asan Medical Center, Seoul, Korea.

Abstract

Chronic progressive external ophthalmoplegia (CPEO) is a rare clinical syndrome characterized by slowly progressive paralysis of extraocular muscles. We report a male patient who had a 20 year history of CPEO. Histological examination of left deltoid muscle showed characteristic ragged red fibers. Electron microscopy revealed a number of abnormal mitochondria which contain paracrystalline inclusion bodies.

Keyword

CPEO; ragged red fibers

MeSH Terms

Biopsy
Chronic Disease
Humans
Male
Middle Aged
Mitochondria/ultrastructure
Muscles/ultrastructure
Ophthalmoplegia/*diagnosis/pathology
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