J Korean Radiol Soc.  2004 Feb;50(2):101-108. 10.3348/jkrs.2004.50.2.101.

Evaluation of Computer Aided Volumetry for Simulated Small Pulmonary Nodules on Computed Tomography

• Do KH
• Chung MJ
• Goo JM
• Lee KW
• Im JG

• KMID: 2103758
• DOI: http://doi.org/10.3348/jkrs.2004.50.2.101

Abstract

PURPOSE: To determine the accuracy of automated computer aided volumetry for simulated small pulmonary nodules at computed tomography using various types of phantoms
MATERIALS AND METHODS
Three sets of synthetic nodules (small, calcified and those adjacent to vessels) were studied. The volume of the nodules in each set was already known, and using multi-slice CT, volumetric data for each nodule was acquired from the three-dimensional reconstructed image. The volume was calculated by applying three different threshold values using Rapidia(R) software (3D-Med, Seoul, Korea).
RESULTS
Relative errors in the measured volume of synthetic pulmonary nodules were 17.3, 2.9, and 11.5% at -200, -400, and -600 HU, respectively, and there was good correlation between true volume and measured volume at -400 HU (r=0.96, p<0.001). For calcified nodules, relative errors in measured volume were 10.9, 5.3, and 16.5% at -200, -400, and -600 HU, respectively, and there was good correlation between true volume and measured volume at -400 HU (r=1.03, p<0.001). In cases involving synthetic nodules adjacent to vessels, relative errors were 4.6, 16.3, and 31.2 % at -200, -400, and -600 HU, respectively. There was good correlation between true volume and measured volume at -200 HU (r=1.1, p<0.001).
CONCLUSION
Using computer-aided volumetry, the measured volumes of synthetic nodules correlated closely with their true volume. Measured volumes were the same at each threshold level, regardless of window setting.

Keyword

Computed tomography (CT), computer programs; Lung, nodule; Lung neoplasms, CT

MeSH Terms

Cone-Beam Computed Tomography
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