J Korean Rheum Assoc.  2003 Dec;10(4):433-437.

A Case of Systemic Lupus Erythematosus with Sensorineural Hearing Loss

Affiliations
  • 1Department of Internal Medicine, College of Medicine, Kyunghee University, Seoul, Korea. yhira@chollian.net

Abstract

Sudden sensorineural hearing loss (SNHL) is a rarely reported clinical manifestation of systemic lupus erythematosus (SLE). Although the exact pathogenesis is still unclear, several reports suggest that circulatory immune complexes or anti-phospholipid antibodies might play a pathological role in hearing impairment in patients with SLE. We describe a 28-year-old female with SLE who presented with sudden SNHL. She was treated with highdose methylprednisolone and plasmapheresis. After 5 times of the plasmapheresis, her hearing ability was improved from 56 dB to 46 dB by measured of pure tone audiometery.

Keyword

Sensorineural hearing loss; Systemic lupus erythematosus; High-dose methylprednisolone; Plasmapheresis

MeSH Terms

Adult
Antibodies
Antigen-Antibody Complex
Female
Hearing
Hearing Loss
Hearing Loss, Sensorineural*
Humans
Lupus Erythematosus, Systemic*
Methylprednisolone
Plasmapheresis
Antibodies
Antigen-Antibody Complex
Methylprednisolone
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