Korean J Anesthesiol.  1990 Aug;23(4):515-519. 10.4097/kjae.1990.23.4.515.

Comparative Study of Vecurnium and Domestic Product of Vecaron in Human

• Shin WJ
• Choi HY
• Yeom JH
• Kim DW
• Jun JH
• Kim KH
• Lee DH
• Kim KS
• Suh JK
• Yoo HK
• Seung IS
• Chon SU

• KMID: 2090548
• DOI: http://doi.org/10.4097/kjae.1990.23.4.515

Abstract

The introduction of musele relaxants was an epoch-making event in the development of clinical anesthesia and their use has hecome essential to anesthesia practice. Vecuronium, one of the newest muscle relaxant, has many advantages; it is rapid and short-acting, noncumulative, has minimal side reactions and is promptly antagonized by anticholinesterases was introduced recently our clinical anesthesia practice. Fortunately, domestic product of vecuronium as vecaron was introduced lately. Therefore, this study was performed to evaluate the effects of vecaron and as compare with vecuronium. The results were as follows: 1) Similar effects of muscle relaxation was observed in both group except the onset time of twitch depression was shorter in vecuronium group than vecaron group. 2) Blood pressure and heart rate was increased during intubation in groups. 3) Recovery index was slightly prolonged in vecuronium group than vecaron group but no significance was observed. However, this recovery index of vecuronium was slightly shorter than previous observations.

Keyword

Muscle relaxant-domestic vecaron; Vecuronium

MeSH Terms

Anesthesia
Blood Pressure
Cholinesterase Inhibitors
Depression
Heart Rate
Humans*
Intubation
Muscle Relaxation
Vecuronium Bromide
Cholinesterase Inhibitors
Vecuronium Bromide