Korean J Dermatol.  1988 Oct;26(5):684-688.

A Case of Acute Graft-versus-Host Disease

• Goo DW
• Lee DS
• Yi JY
• Cho BK
• Houh W
• Kim CC

Abstract

We report a case of acute graft-versus-host disease, which developed after bone marrow transplantation because of acute myelocytic leukemia in a 39-year old male, The pruritic, erythematous maculopapular eruptions began to developed on the perioral regions, and spreaded the face, the oral mucosa, both hands, and buttocks at the twenty fourth day after bone marrow transplanta.tion. The eruptions were confluent to form erythematous patches. Iistopathological findings show parakeratosis, lymphoid cell exocytosis, and papillary edema, lymphohistiocytic infiltration, and melanophage in the upper dermis, and basal vacuolation. He was treated systemically by methylprednisolone, and antilymphocytic globulin, and tapically by emollients and steroids.

Keyword

Actue graft-versus-host disease; Antilymphocytic globulin

MeSH Terms

Adult
Bone Marrow
Bone Marrow Transplantation
Buttocks
Dermis
Edema
Emollients
Exocytosis
Graft vs Host Disease*
Hand
Humans
Leukemia, Myeloid, Acute
Lymphocytes
Male
Methylprednisolone
Mouth Mucosa
Parakeratosis
Steroids
Emollients
Methylprednisolone
Steroids