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[ 64 Cu]Cu-Albumin Clearance Imaging to Evaluate Lymphatic Efflux of Cerebrospinal Space Fluid in Mouse Model

Sarker A, Suh M, Choi Y, Park JY, Kwon S, Kim H, Lee E, Seo H, Lee YS, Lee DS

Purpose Clearance of brain waste in the cerebrospinal fluid (CSF) through the meningeal lymphatic vessels (mLV) has been evaluated mostly through the fluorescent imaging which has inherent limitations in the...
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Factors influencing patterns of recurrence following pancreaticoduodenectomy for patients with distal bile duct cancer and ampulla of Vater cancer

Lee DH, Kim HJ, Cho CW, Yun SS, Lee DS

Backgrounds/Aims: Pancreaticoduodenectomy (PD) is a standard surgical procedure for patients with periampullary cancer. During the follow-up period after PD, recurrence can be observed in various places with different prognosis. The...
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Osteoporosis Is Associated with an Increased Risk of Colorectal Adenoma and High-Risk Adenoma: A Retrospective, Multicenter, Cross-Sectional, Case-Control Study

Nam JH, Koh M, Kang HW, Ryu KH, Lee DS, Kim SH, Jang DK, Jeong JB, Kim JW, Lee KL, Oh DJ, Lim YJ, Koh SJ, Im JP, Kim JS

Background/Aims: The protective effects of vitamin D and calcium on colorectal neoplasms are known. Bone mineral density (BMD) may be a reliable biomarker that reflects the long-term anticancer effect of...
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The additional analgesic effects of transverse abdominis plane block in patients receiving low-dose intrathecal morphine for minimally invasive colorectal surgery: a randomized, single-blinded study

Han SR, Lee CS, Bae JH, Lee HJ, Yoon MR, Lee DS, Lee YS, Al-Sawat A, Shim JW, Hong SH, Lee IK

Purpose: Intrathecal analgesia (ITA) and transverse abdominis plane block (TAPB) are effective pain control methods in abdominal surgery. However, there is still no gold standard for postoperative pain control in...
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Letter to the Editor: How Can We Predict a Successful Outcome after Varicocelectomy in Painful Varicocele Patients? An Updated MetaAnalysis

Shin YS, Lee DS

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Inhibitory effect of mangosteen peel and propolis ethanol extracts on alveolar bone loss against increased treatment amount of Porphyromonas gingivalis lipopolysaccharide in rat

Lee KH, Yoo SY, Kook JK, Sung SJ, Lee KW, Lim YK, Lee DS, Yu SJ

In previous studies, we introduced that mangosteen extract complex (MEC; ethanol extracts of Garcinia mangostana L. peel and propolis) had inhibitory effects on inflammation and alveolar bone loss in silk-ligature...
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The Effects of Exercise Intervention for Post-Operative Breast Cancer Patients in Korea: A Systemic Review and Meta-Analysis of Randomized Controlled Trials

Lee Ds, Kim Hs, Choi So, Kim Em

Purpose: This study aimed to systematically evaluate literature related to the effects of exercise intervention programs on physical or psychological variables of post-operative breast cancer patients in Korea, and identify...
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Analysis of avoidable cardiopulmonary resuscitation incidents with a part-time rapid response system in place

Cho JY, Lee DS, Choi YY, Park JS, Cho YJ, Yoon HI, Lee JH, Lee CT, Lee YJ

Background: Although a rapid response system (RRS) can reduce the incidence of cardiopulmonary resuscitation (CPR) in general wards, avoidable CPR cases still occur. This study aimed to investigate the incidence...
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Association between Nocturnal Frequency and Erectile Function in Eugonadal Men with Benign Prostatic Obstruction: A Cross Sectional Study

Lee DS, Kim SW, Sohn DW

Purpose: We aimed to evaluate the association between nocturnal frequency and erectile dysfunction in patients with benign prostatic obstruction. Materials and Methods: To evaluate the association, we simultaneous evaluated urodynamic study,...
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The antibacterial effect of Endoseal TCS mixed with water-soluble mangostin derivatives of Garcinia mangostana L. ethanol extract against Enterococcus faecalis and Staphylococcus aureus

Park TY, Lim YK, Kim JH, Lee DS, Kook JK

This study evaluated the antimicrobial activity of Endoseal TCS, an mineral trioxide aggregate-based root canal sealer, mixed with water-soluble mangostin derivatives (WsMD) of Garcinia mangostana L. (mangosteen) ethanol extract against...
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Alpha-lipoic acid protects human dopaminergic neuronal cells against hydrogen peroxide-induced cell injury by inhibiting autophagy and apoptosis

Kang KR, Kim JS, Kim TH, Seo JY, Lim H, Park JH, Yang KY, Yu SK, Kim HJ, Kim CS, Chun HS, Lee DS, Park JC, Kim DK

Alpha-lipoic acid (ALA) is a naturally occurring antioxidant and has been previously used to treat diabetes and cardiovascular disease. However, the autophagy effects of ALA against oxidative stress-induced dopaminergic neuronal...
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Increased Risk of Pancreatitis after Endoscopic Retrograde Cholangiopancreatography Following a Positive Intraoperative Cholangiogram: A Single-Center Experience

Sitaraman LM, Knotts RM, Kim J, Mahadev S, Lee DS

Background/Aims: To determine if patients with a positive intraoperative cholangiogram (IOC) who undergo a subsequent endoscopic retrograde cholangiopancreatography (ERCP) have an increased risk of post-ERCP pancreatitis (PEP) compared to those...
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Expression of Chemokine CCL28 in Ulcerative Colitis Patients

Lee DS, Lee KL, Jeong JB, Shin S, Kim SH, Kim JW

Background/Aims: Ulcerative colitis (UC) is an inflammatory bowel disease for which new serological markers are required. The purpose of this study was to assess the role of the mucosaassociated epithelial...
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Post-mastectomy radiation therapy in breast reconstruction: a patterns of care study of the Korean Radiation Oncology Group

Yang G, Chang JS, Shin KH, Kim JH, Park W, Kim H, Kim K, Lee IJ, Yoon WS, Cha J, Lee KC, Kim JH, Choi JH, Ahn SJ, Ha B, Lee SY, Lee DS, Lee J, Shin SO, Kim YB

Purpose: The details of breast reconstruction and radiation therapy (RT) vary between institutions; therefore, we sought to investigate the practice patterns of radiation oncologists who specialize in breast cancer. Materials and...
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A Comparison of Short-Term Outcomes between Laparoscopic and Open Liver Resection in Elderly Patients

Lee SY, Lee DS, Yun SS, Cho CW

Purpose: The aim of this study was to compare the short-term outcomes between laparoscopic liver resection (LLR) and open liver resection (OLR) in elderly patients with hepatic tumors. Methods: From January...
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Spatial Normalization Using Early-Phase [ 18F]FP-CIT PET for Quantification of Striatal Dopamine Transporter Binding

Bae S, Choi H, Whi W, Paeng JC, Cheon GJ, Kang KW, Lee DS

Purpose The precise quantification of dopamine transporter (DAT) density on N-(3-[18F]Fluoropropyl)-2β-carbomethoxy-3β-(4-iodophenyl) nortropane positron emission tomography ([18F]FP-CIT PET) imaging is crucial to measure the degree of striatal DAT loss in patients with...
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Clinical outcome and predictive factors for docetaxel and epirubicin neoadjuvant chemotherapy of locally advanced breast cancer

Won HS, Kim YS, Kim JS, Chang ED, Na SJ, Whang IY, Lee DS

Background/Aims: We evaluated the efficacy of docetaxel and epirubicin as neoadjuvant chemotherapy in locally advanced breast cancer and assessed the predictive factors for response to neoadjuvant chemotherapy and prognostic factors...
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Impaired Hand Dexterity Function in a Non-human Primate Model with Chronic Parkinson’s Disease

Seo Jc, Won Jy, Kim Kw, Park Jh, Yeo HG, Kim YG, Baek SH, Lee H, Jeon CY, Choi WS, Lee S, Kim KJ, Park SH, Son Yh, Jeong KJ, Lim KS, Kang P, Lee HY, Son HC, Huh JW, Kim YH, Lee DS, Lee SR, Choi JW, Lee Yj

  • KMID: 2508474
  • Exp Neurobiol.
  • 2020 Oct;29(5):376-388.
  • doi: 10.5607/en20040
ymptoms of Parkinson’s disease (PD) caused by loss of dopaminergic neurons are accompanied by movement disorders, including tremors, rigidity, bradykinesia, and akinesia. Non-human primate (NHP) models with PD play an...
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Brain Glymphatic/Lymphatic Imaging by MRI and PET

Lee DS, Suh M, Sarker A, Choi Y

Since glymphatic was proposed and meningeal lymphatic was discovered, MRI and even PET were introduced to investigate brain parenchymal interstitial fluid (ISF), cerebrospinal fluid (CSF), and lymphatic outflow in rodents...
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Efficacy and Safety of Testosterone Therapy Based on Guideline Recommendations; Re: Clinical Practice Guideline by the American College of Physicians

Lee DS, Park HJ

No abstract available.
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