Korean J Gastrointest Endosc.  2008 Jun;36(6):361-365.

A Case of Esophageal Benign Schwannoma Removed by Endoscopic Mucosal Resection

• Cho S
• Park CH
• Ryang DY
• Lim SR
• Chung KM
• Jeong HK
• Jung PJ
• Lee SH
• Yoon KW
• Kim HS
• Choi SK
• Rew JS

Abstract

Esophageal schwannoma is a very rare neoplasm. The differentiation of schwannoma from the other submucosal tumors such as GISTs or leiomyoma is very difficult to do on the preoperative examination with performing esophagoscopy and computed tomography. The diagnosis is generally not confirmed until the histologic and immunohistochemical tests of the tumor are performed. A 38- year-old man presented to us with neck discomfort. The endoscopy showed a middle esophageal submucosal tumor that measured 12 mm in size and there were no mucosal changes. The endoscopic ultrasonography showed a tumor in the muscluaris mucosa layer without lymphadenopathy. After band ligation of the lower part of the tumor, it was removed by performing endoscopic mucosal resection and using a snare. A definitive diagnosis of esophageal benign schwannoma was made from the pathologic findings, which included positive immunohistochemical staining for S-100 protein and negative staining for C-kit, CD34 and actin. We report here on an esophageal benign schwannoma that was removed by endoscopic mucosal resection.

Keyword

Esophageal schwannoma; S-100 protein; Endoscopic mucosal resection

MeSH Terms

Actins
Endoscopy
Endosonography
Esophagoscopy
Leiomyoma
Ligation
Lymphatic Diseases
Mucous Membrane
Neck
Negative Staining
Neurilemmoma
S100 Proteins
SNARE Proteins
Actins
S100 Proteins
SNARE Proteins