Korean J Gastrointest Endosc.  2003 Mar;26(3):167-171.

A Case of Mucin-hypersecreting Biliary Papillomatosis: Including Review of Korean Literatures

Affiliations
  • 1Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. mhkim@www.amc.seoul.kr
  • 2Department of Diagnostic Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.

Abstract

The mucin-hypersecreting bile duct tumor is rare and its clinical, radiologic, and pathologic features are not well known. We report the case of mucin-hypersecreting biliary papillomatosis with malignant transformation including review of 11 korean literatures. A 65-year-old female was admitted to our hospital with fever, chills, and right upper quadrant pain. A CT scan showed marked dilatation of left intrahepatic duct with intraductal filling defects. During endoscopic retrograde cholangiograpy, mucin from the ampulla was observed and dilated common bile duct with multiple amorphous filling defects was noted. Cholangioscopy revealed muliple coral-like mucosal papillary projections with large amount of mucin in the left intrahepatic ducts. The patient underwent left lobectomy, and the biopsy revealed intraductal papillary adenocarcinoma in the background of papillary adenoma.

Keyword

Mucin-hypersecreting; Biliary papillomatosis; Adenocarcinoma

MeSH Terms

Adenocarcinoma
Adenocarcinoma, Papillary
Adenoma
Aged
Bile Ducts
Biopsy
Chills
Common Bile Duct
Dilatation
Female
Fever
Humans
Mucins
Papilloma*
Tomography, X-Ray Computed
Mucins
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