Korean J Med.  2005 Jan;68(1):105-110.

Two Cases Of Primary Hepatocellular Carcinoma With Skull Metastasis

• Kim YS
• Kim YS
• Kim YS
• Lee MS
• Hong DS
• Shim CS
• Kim BS

Abstract

Primary hepatocellular carcinoma (HCC) is one of the most common tumors in the world. HCC often metastases to the lung and the regional lymph nodes, but rarely to the bones. The most frequent sites of skeletal metastasis are the rib, spine, femur, pelvis and humerus, but the metastasis to the skull is very rare in HCC. Especially, the metastasis to the skull alone, or skull mass presented as first sign in HCC is extremely rare. We report a 74-year-old female who had HCC with the solitary skull metastasis and a 42-year-old male with HCC presented skull metastasis as the initial clinical manifestation.

Keyword

Hepatocellular carcinoma; Skull metastasis

MeSH Terms

Adult
Aged
Carcinoma, Hepatocellular*
Female
Femur
Humans
Humerus
Lung
Lymph Nodes
Male
Neoplasm Metastasis*
Pelvis
Ribs
Skull*
Spine