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The Distinctive Immunologic Pathogenesis Differentiates Atopic Comorbidity Status in Prurigo Nodularis

Chu H, Kim WJ, Kim SM, Kim SH, Kim JH, Zhang K, Kim HL, Kim RW, Lee KH, Park CO

  • KMID: 2538563
  • Korean J Dermatol.
  • 2022 Dec;60(10):666-674.
Background: Prurigo nodularis (PN) is a chronic pruritic skin disorder with a large number of hyperkeratotic nodules. The precise mechanisms of its pathogenesis remain unknown. PN has been linked to...
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Structural Equation Modeling Based on PRECEDE Model for the Quality of Life in the Elderly with Dementia in Rural Area

Song MS, Kim HL

Purpose: This study was designed to test structural equation modeling of the quality of life of elderly diagnosed dementia living in the community in order to provide guidelines for development...
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Awareness Survey on Community Water Fluoridation by Region

Joung YE, Kim MH, Kim HL, Baek JY, Jang YJ, Choi JY, Oh SH

Background: The purpose of this study is to investigate the pro-con of re-implementation by administrative areas and the difference in perception of community water fluoridation in implemented and non-implemented areas...
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Renal cell carcinoma in pretransplant native nephrectomy of hemodialysis patient with acquired cystic kidney disease for deceased donor renal transplantation

Shin BC, Shin MH, Yoon YM, Kim HL, Chung JH, Choi NG

The incidence of renal cell carcinoma is known to be higher in patients with end-stage renal disease, including those with acquired cystic kidney disease. Pretransplant native nephrectomy is performed to...
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Microneedle Transdermal Drug Delivery Systems for Allergen-Specific Immunotherapy, Skin Disease Treatment, and Vaccine Development

Park CO, Kim HL, Park JW

Transdermal drug delivery systems (TDDSs) overcome the hurdle of an intact skin barrier by penetrating the skin to allow molecules through. These systems reduce side effects associated with conventional hypodermic...
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Elevated On-Treatment Diastolic Blood Pressure and Cardiovascular Outcomes in the Presence of Achieved Systolic Blood Pressure Targets

Kim DH, Cho IJ, Kim W, Lee CJ, Kim HC, Shin JH, Kang SH, Jung MH, Kwon CH, Lee JH, Kim HL, Kim HM, Cho I, Kang DR, Lee HY, Chung WJ, Kim KI, Cho EJ, Sohn IS, Park S, Shin J, Ryu SK, Kang SM, Pyun WB, Cho MC, Kim JH, Lee JH, Ihm SH, Sung KC

Background and Objectives: This study aimed to investigate the association between cardiovascular events and 2 different levels of elevated on-treatment diastolic blood pressures (DBP) in the presence of achieved systolic...
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Interventions for Adherence Improvement in the Primary Prevention of Cardiovascular Diseases: Expert Consensus Statement

Ihm SH, Kim KI, Lee KJ, Won JW, Na JO, Rha SW, Kim HL, Kim SH, Shin J

In primary prevention for cardiovascular diseases, there are significant barriers to adherence including freedom from symptoms, long latency for therapeutic benefits, life-long duration of treatment, and need for combined lifestyle...
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Deep Learning-Based Algorithm for the Detection and Characterization of MRI Safety of Cardiac Implantable Electronic Devices on Chest Radiographs

Kim UH, Kim MY, Park EA, Lee W, Lim WH, Kim HL, Oh S, Jin KN

Objective: With the recent development of various MRI-conditional cardiac implantable electronic devices (CIEDs), the accurate identification and characterization of CIEDs have become critical when performing MRI in patients with CIEDs....
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Incidental renal cell carcinoma in a native kidney of patient with autosomal dominant polycystic kidney disease for renal transplantation: a case report

Shin BC, Shin MH, Kim HL, Chung JH, Choi NG

Background: Autosomal dominant polycystic kidney disease (ADPKD) is an important cause of end-stage renal disease. Pretransplant native nephrectomy is performed to create space in the pelvis, to decrease compression by...
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Light chain deposition disease in kidney transplantation: a case report

Shin BC, Kim HL, Chung JH

Background: The light chain deposition disease (LCDD) is a range from normal glomerular morphology to mesangioproliferative to mesangiocapillary to nodular sclerosing patterns. Due to the inconsistencies treatment and the poor...
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Water-soluble coenzyme Q10 provides better protection than lipid-soluble coenzyme Q10 in a rat model of chronic tacrolimus nephropathy

Cui S, Luo K, Quan Y, Lim SW, Shin YJ, Lee KE, Kim HL, Ko EJ, Kim JH, Chung SJ, Bae SK, Chung BH, Yang CW

Background/Aims: Coenzyme Q10 (CoQ10), is a promising antioxidant; however, low bioavailability owing to lipid-solubility is a limiting factor. We developed water-soluble CoQ10 (CoQ10-W) and compared its effects with conventional lipid-soluble...
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Analysis of Medical Use and Treatment Costs of Hepatocellular Carcinoma Patients Using National Patient Sample Data

Oh BC, Cho JY, Kwon SH, Lee EK, Kim HL

Background: With increasing economic evaluation studies on the treatment of or screening tools for liver diseases that cause hepatocellular carcinoma (HCC), interest in the analysis of the medical utilization and...
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A new perspective on calcium channel blockers in vasospastic angina

Kim HL

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Associations between measurements of central blood pressure and target organ damage in high-risk patients

Jeon KH, Kim HL, Lim WH, Seo JB, Kim SH, Zo JH, Kim MA

Background: It is not well-known which components of central blood pressure (CBP) are more influential to target organ damage (TOD). This study aimed to determine the relationship between CBP measurements...
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Usefulness of Nested Polymerase Chain Reaction with Clinical Specimens for Diagnosis of Leptospirosis: a Case Series and a Review of Literature

Na YS, Kim HL, Kim CM, Yun NR, Kim DM

A culture of the Leptospira species and the microscopic agglutination test (MAT) are considered as the reference standard for the diagnosis of leptospirosis, but both tests are imperfect for early...
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Factors Associated with Low Awareness of Heart Failure in the General Population of Korea

Kim HL, Jung MH, Choi JH, Lee S, Kong MG, Na JO, Cho YH, Cho KI, Choi DJ, Kim EJ

Background and Objectives: Factors associated with low heart failure (HF) awareness have not been well-evaluated. This study was conducted to find out which demographic features would be associated with low...
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Gender differences in the presentation of chest pain in obstructive coronary artery disease: results from the Korean Women’s Chest Pain Registry

Cho DH, Choi J, Kim MN, Kim HL, Kim YH, Na JO, Jeong JO, Yoon HJ, Shin MS, Kim MA, Hong KS, Shin GJ, Park SM, Shim WJ

Background/Aims: Chest pain in patients with obstructive coronary artery disease (OCAD) is affected by several social factors. The gender-based differences in chest pain among Koreans have yet to be investigated. Methods:...
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Effect of saccharin on inflammation in 3T3-L1 adipocytes and the related mechanism

Kim HL, Ha AW, Kim WK

BACKGROUND/OBJECTIVES: Excessive intake of simple sugars induces obesity and increases the risk of inflammation. Thus, interest in alternative sweeteners as a sugar substitute is increasing. The purpose of this study...
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Spatiotemporal Profile and Morphological Changes of NG2 Glia in the CA1 Region of the Rat Hippocampus after Transient Forebrain Ischemia

Jin X, Riew TR, Kim S, Kim HL, Lee MY

Neuron-glial antigen-2 (NG2) glia undergo proliferation and morphological changes following brain insults. Here, we show that NG2 glia is activated in a characteristic time- and layer-specific manner in the ischemia-vulnerable...
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It is time to focus on pre-hospital delays in patients with ST-segment elevation myocardial infarction

Kim HL

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