Korean J Nucl Med.  2003 Oct;37(5):325-330.

Chorea in Systemic Lupus Erythematosus: Evidence for Bilateral Putaminal Hypermetabolism on F-18 FDG PET

Affiliations
  • 1Department of Internal Medicine, Universitiy of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. byoo@amc.seoul.kr
  • 2Department of Nuclear Medicine, Universitiy of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
  • 3Department of Neurology, Universitiy of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.

Abstract

PURPOSE
We describe a 54-year-old woman with systemic lupus erythematosus (SLE) who suddenly presented with chorea and had positive antiphospholipid antibodies. F-18 FDG PET showed abnormally increased glucose metabolism in bilateral putamen and primary motor cotex. Tc-99m ECD SPECT also showed abnormally increased regional cerebral blood flow in bilateral putamen. She was treated with corticosteroid and aspirin after which the symptoms improved. Four months later, follow up F-18 FDG PET showed improvement with resolution of hypermetabolism in bilateral putamen. This case suggests that striatal hypermetabolism is associated with chorea in SLE.

Keyword

Systemic lupus erythematosus; Chorea; F-18 FDG; PET

MeSH Terms

Antibodies, Antiphospholipid
Aspirin
Chorea*
Female
Follow-Up Studies
Glucose
Humans
Lupus Erythematosus, Systemic*
Metabolism
Middle Aged
Putamen
Tomography, Emission-Computed, Single-Photon
Antibodies, Antiphospholipid
Aspirin
Glucose
Full Text Links
  • KJNM
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr