J Korean Neurol Assoc.
1999 Sep;17(5):764-766.
Two Cases of Marchiafava-Bignami Disease
- Affiliations
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- 1Department of Neurology, Chonbuk National University Medical School.
- 2Institute for Medical Sciences.
Abstract
- We described 2 patients with Marchiafava-Bignami disease, a neurological disorder associated with chronic alcohol consumption. Patient 1 expressed general weakness and confusion, while patient 2 expressed dysphagia and seizures. Lesions involving the corpus callosum were identified with T2 weighted MR imaging in which there was a hyperintensity in the splenium of patient 1 and in the entire corpus callosum of patient 2. While the conditions of both patients were improved by with nutritional support, they were left with cognitive impairment.
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