J Korean Diabetes Assoc.
1999 Dec;23(6):822-830.
The Difference of Intrarenal Hemodynamics in Type 2 Diabetic Nephropathy
Abstract
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BACKGROUND: Diabetic nephropathy is a major microvascular complication in diabetic patients. No single etiologic
factor has been identified to explain the development of diabetic nephropathy. Genetic factors, poor glycemic control,
increased intra-glomerular pressure, systemic hypertension, and altered intrarenal hemodynamics may be contributed to
the pathogenesis of diabetic nephropathy. Intrarenal duplex Doppler sonography can provide physiologic information
reflecting the status of renal vascular resistance. Recently, there were some reports that obstructive renal disease
and renal allograft rejection patients has altered intrarenal hemodynamics. So we investigate intrarenal hemo- dynamic
abnormalities in diabetic patients with nephropathy and analyze the factors associated with increased intrarenal
resistance METHODS: The patients were divided into the three groups. According to the levels of 24-hour urinary albumin
excretion(UAE), group 1 (UAE<30mg/day, normoalbuminuria), group 2 (30 mg/day
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