- Diabetic kidney disease: seven questions
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Yang DH, Lee SY
- KMID: 2467980
- J Korean Med Assoc.
- 2020 Jan;63(1):6-13.
- doi: 10.5124/jkma.2020.63.1.6
Diabetic kidney disease is a microvascular complication of diabetes mellitus and the leading cause of end-stage renal disease resulting in renal replacement therapy. Approximately 30% to 40% of diabetic patients... -
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- Progression of diabetic nephropathy after successful pancreas transplantation alone: a case report
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Kim Y, Kim DI, Shim JR, Lee TB, Yang KH, Ryu JH, Lee HJ, Choi BH
- KMID: 2468165
- Korean J Transplant.
- 2019 Dec;33(4):146-152.
- doi: 10.4285/jkstn.2019.33.4.146
Pancreas transplantation is the only method that can nearly cure insulin-dependent diabetes mellitus. However, the effect of pancreas transplantation on patients with diabetic nephropathy has recently been considered controversial. In... -
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- Self-Care of Diabetic Nephropathy
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Shin UJ
- KMID: 2458967
- J Korean Diabetes.
- 2019 Sep;20(3):176-180.
- doi: 10.4093/jkd.2019.20.3.176
Early intervention in patients with diabetes may slow the progression of kidney disease, and early recognition of renal impairment is critical to achieving optimal patient outcomes. Annual screening for the... -
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- Associations between the HaeIII Single Nucleotide Polymorphism in the SLC2A1 Gene and Diabetic Nephropathy in Korean Patients with Type 2 Diabetes Mellitus
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Lee DH, Won GW, Lee YH, Ku EJ, Oh TK, Jeon HJ
- KMID: 2449986
- J Korean Med Sci.
- 2019 Jun;34(24):e171.
- doi: 10.3346/jkms.2019.34.e171
BACKGROUND: Diabetic nephropathy (DN) is the most serious microvascular complication of diabetes mellitus and is one of the leading causes of end stage renal failure. In previous studies, the contribution... -
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- Adiponectin for the treatment of diabetic nephropathy
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Lee JY, Yang JW, Han BG, Choi SO, Kim JS
- KMID: 2448339
- Korean J Intern Med.
- 2019 May;34(3):480-491.
- doi: 10.3904/kjim.2019.109
The metabolic burden caused by hyperglycemia can result in direct and immediate metabolic injuries, such as oxidative stress and tissue inflammation, in the kidney. Furthermore, chronic hyperglycemia can lead to... -
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- Predictive Factors for Efficacy of AST-120 Treatment in Diabetic Nephropathy: a Prospective Single-Arm, Open-Label, Multi-Center Study
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Hwang YC, Kim SW, Hur KY, Cha BS, Kim IJ, Park TS, Baik SH, Yoon KH, Lee KW, Lee IK, Lee MK
- KMID: 2443205
- J Korean Med Sci.
- 2019 Apr;34(15):e117.
- doi: 10.3346/jkms.2019.34.e117
BACKGROUND: Removal of uremic toxins such as indoxyl sulfate by AST-120 is known to improve renal function and delay the initiation of dialysis in patients with advanced chronic kidney disease.... -
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- Diabetic Nephropathy in Type 2 Diabetic Retinopathy Requiring Panretinal Photocoagulation
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Ha M, Choi SY, Kim M, Na JK, Park YH
- KMID: 2434304
- Korean J Ophthalmol.
- 2019 Feb;33(1):46-53.
- doi: 10.3341/kjo.2018.0034
PURPOSE: To investigate the risk factors of diabetic nephropathy in patients with diabetic retinopathy requiring panretinal photocoagulation (PRP) and the visual prognosis. METHODS: A retrospective review of electronic medical records was... -
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- Plasma Neutrophil Gelatinase-Associated Lipocalin as a Marker of Tubular Damage in Diabetic Nephropathy
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Kim SY, Jeong TD, Lee W, Chun S, Sunwoo S, Kim SB, Min WK
- KMID: 2429117
- Ann Lab Med.
- 2018 Nov;38(6):524-529.
- doi: 10.3343/alm.2018.38.6.524
BACKGROUND: An increase in neutrophil gelatinase-associated lipocalin (NGAL) indicates tubular injury. Diabetic nephropathy causes typical changes in the kidney, characterized by glomerulosclerosis and eventual tubular damage. We validated the usefulness... -
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- Use of dapagliflozin in patients with advanced diabetic kidney disease
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Park HS, Jung YJ, Lee DY, Moon KH, Kim B, Kim HW
- KMID: 2447169
- Kidney Res Clin Pract.
- 2018 Sep;37(3):292-297.
- doi: 10.23876/j.krcp.2018.37.3.292
Sodium-glucose cotransporter-2 (SGLT2) inhibitors are effective for overweight diabetic patients through the induction of glucosuria. However, SGLT2 inhibitors are not recommended for patients with advanced chronic kidney disease (CKD) because... -
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- Noncoding RNAs as therapeutic targets in early stage diabetic kidney disease
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Kato M
- KMID: 2447159
- Kidney Res Clin Pract.
- 2018 Sep;37(3):197-209.
- doi: 10.23876/j.krcp.2018.37.3.197
Diabetic kidney disease (DKD) is a major renal complication of diabetes that leads to renal dysfunction and end-stage renal disease (ESRD). Major features of DKD include accumulation of extracellular matrix... -
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- Pathology identifies glomerular treatment targets in diabetic nephropathy
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Alpers CE, Hudkins KL
- KMID: 2416078
- Kidney Res Clin Pract.
- 2018 Jun;37(2):106-111.
- doi: 10.23876/j.krcp.2018.37.2.106
The development of the glomerular injury in diabetic nephropathy involves interactions between podocytes, endothelium, and the mesangium. Loss of podocytes is an early and critical step in the development of... -
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- Glycated Albumin Is a More Useful Glycation Index than HbA1c for Reflecting Renal Tubulopathy in Subjects with Early Diabetic Kidney Disease
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Huh JH, Lee M, Park SY, Kim JH, Lee BW
- KMID: 2413984
- Diabetes Metab J.
- 2018 Jun;42(3):215-223.
- doi: 10.4093/dmj.2017.0091
BACKGROUND: The aim of this study was to investigate which glycemic parameters better reflect urinary N-acetyl-β-D-glucosaminidase (uNAG) abnormality, a marker for renal tubulopathy, in subjects with type 2 diabetes mellitus... -
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- Recent Updates on Diabetic Nephropathy
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Kee YK, Han SH
- KMID: 2411420
- J Korean Diabetes.
- 2017 Dec;18(4):214-228.
- doi: 10.4093/jkd.2017.18.4.214
Diabetic nephropathy is a common complication of diabetes mellitus and is the leading cause of chronic kidney disease. Glycemic and blood pressure control constitute the main strategies of diabetic nephropathy... -
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- p22phox C242T gene polymorphism and overt diabetic nephropathy: a meta-analysis of 1,452 participants
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Li YY, Gong G, Geng HY, Qian Y
- KMID: 2396764
- Korean J Intern Med.
- 2017 Nov;32(6):1045-1052.
- doi: 10.3904/kjim.2015.106
BACKGROUND/AIMS: The p22phox C242T gene polymorphism (rs4673) may be linked to an increased susceptibility for overt diabetic nephropathy (ODN), but the study results are still inconclusive. METHODS: To explore the relationship... -
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- Treatment of diabetic kidney disease: current and future targets
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Kim MK
- KMID: 2387706
- Korean J Intern Med.
- 2017 Jul;32(4):622-630.
- doi: 10.3904/kjim.2016.219
Diabetic kidney disease (DKD) is a leading cause of end-stage renal disease in Korea and worldwide, and is a risk factor for the development of cardiovascular complications. The conventional treatments... -
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- Mesenchymal Stem Cell-Based Therapies against Podocyte Damage in Diabetic Nephropathy
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Khalilpourfarshbafi M, Hajiaghaalipour F, Krishnan Selvarajan K, Adam A
- KMID: 2395077
- Tissue Eng Regen Med.
- 2017 Jun;14(3):201-210.
- doi: 10.1007/s13770-017-0026-5
Injury to podocytes is an early event in diabetic nephropathy leading to proteinuria with possible progression to end-stage renal failure. The podocytes are unique and highly specialized cells that cover... -
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- Interleukin-20 targets podocytes and is upregulated in experimental murine diabetic nephropathy
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Hsu YH, Li HH, Sung JM, Chen WY, Hou YC, Weng YH, Lai WT, Wu CH, Chang MS
- KMID: 2375797
- Exp Mol Med.
- 2017 Mar;49(3):e310.
- doi: 10.1038/emm.2016.169
Interleukin (IL)-20, a proinflammatory cytokine of the IL-10 family, is involved in acute and chronic renal failure. The aim of this study was to elucidate the role of IL-20 during... -
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- New therapeutic agents in diabetic nephropathy
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Kim Y, Park CW
- KMID: 2365975
- Korean J Intern Med.
- 2017 Jan;32(1):11-25.
- doi: 10.3904/kjim.2016.174
Studies investigating diabetic nephropathy (DN) have mostly focused on interpreting the pathologic molecular mechanisms of DN, which may provide valuable tools for early diagnosis and prevention of disease onset and... -
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- Nonalbuminuric Renal Insufficiency: Can It Be a Novel Category of Diabetic Nephropathy?
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Tanaka M, Itoh H
- KMID: 2373072
- Endocrinol Metab.
- 2016 Dec;31(4):533-534.
- doi: 10.3803/EnM.2016.31.4.533
No abstract available. -
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- Risk Factors for the Development and Progression of Diabetic Kidney Disease in Patients with Type 2 Diabetes Mellitus and Advanced Diabetic Retinopathy
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Yun KJ, Kim HJ, Kim MK, Kwon HS, Baek KH, Roh YJ, Song KH
- KMID: 2362220
- Diabetes Metab J.
- 2016 Dec;40(6):473-481.
- doi: 10.4093/dmj.2016.40.6.473
BACKGROUND: Some patients with type 2 diabetes mellitus (T2DM) do not develop diabetic kidney disease (DKD) despite the presence of advanced diabetic retinopathy (DR). We aimed to investigate the presence... -
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