Clin Endosc.  2012 Mar;45(1):25-43. 10.5946/ce.2012.45.1.25.

Korean Guidelines for Colorectal Cancer Screening and Polyp Detection

• Lee BI
• Hong SP
• Kim SE
• Kim SH
• Kim HS
• Hong SN
• Yang DH
• Shin SJ
• Lee SH
• Park DI
• Kim YH
• Kim HJ
• Yang SK
• Kim HJ
• Jeon HJ
• Multi-Society Task Force for Development of Guidelines for Colorectal Polyp Screening, Surveillance and Management

• KMID: 2048831
• DOI: http://doi.org/10.5946/ce.2012.45.1.25

Abstract

Now colorectal cancer is the second most common cancer in males and the fourth most common cancer in females in Korea. Since most of colorectal cancers occur after the prolonged transformation of adenomas into carcinomas, early detection and removal of colorectal adenomas are one of the most effective methods to prevent colorectal cancer. Considering the increasing incidence of colorectal cancer and polyps in Korea, it is very important to establish Korean guideline for colorectal cancer screening and polyp detection. The guideline was developed by the Korean Multi-Society Take Force and we tried to establish the guideline by evidence-based methods. Parts of the statements were draw by systematic reviews and meta-analyses. Herein we discussed epidemiology of colorectal cancers and adenomas in Korea and optimal methods for screening of colorectal cancer and detection of adenomas including fecal occult blood tests, radiologic tests, and endoscopic examinations.

Keyword

Early detection of cancer; Colorectal neoplasms; Occult blood; Colonoscopy; Computed tomographic colonography

MeSH Terms

Adenoma
Colonography, Computed Tomographic
Colonoscopy
Colorectal Neoplasms
Early Detection of Cancer
Female
Humans
Incidence
Korea
Male
Mass Screening
Occult Blood
Polyps

Figure

• 

  Fig. 1 Study selection. DCBE, double-contrast barium enema; CTC, computed tomography colonography; FSG, flexible sigmoidoscopy; CS, colonoscopy; RCT, randomized controlled trial.

• 

  Fig. 2 Meta-analysis of the detection rate of fecal immunochemical test (FIT) for advanced colorectal neoplasms according to the number of samples (1 test vs. 2 tests). CI, confidence interval.

• 

  Fig. 3 Meta-analysis comparing guaiac based fecal occult blood testing and fecal immunochemical test in the detection of colorectal cancer in average-risk groups. gFOBT, guaiac based fecal occult blood testing; CI, confidence interval.

• 

  Fig. 4 Meta-analysis of reported sensitivity and specificity in the included studies by polyp size. (A) Per-patient sensitivity for computed tomography (CT) colonography. (B) Per-patient specificity for CT colonography. (C) Per-polyp sensitivity for CT colonography. CI, confidence interval.

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