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Hsa_circ_0003602 Contributes to the Progression of Colorectal Cancer by Mediating the miR-149-5p/SLC38A1 Axis

Wu R, Tang S, Wang Q, Kong P, Liu F

Background/Aims: We aimed to investigate the role and working mechanism of Homo sapiens circular RNA_0003602 (hsa_circ_0003602) in colorectal cancer (CRC) development. Methods: The expression of circ_0003602, miR-149-5p, and solute carrier family...
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Analysis of the gut microbiome using extracellular vesicles in the urine of patients with colorectal cancer

Yoon H, Kim NE, Park J, Shin CM, Kim N, Lee DH, Park JY, Choi CH, Kim JG, Park YS

Background/Aims: We evaluated the gut microbiome using extracellular vesicles (EVs) in the urine of patients with colorectal cancer (CRC) to determine whether gut-microbe-derived EVs could be a potential biomarker for...
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Universal Screening for Lynch Syndrome Compared with Pedigree-Based Screening: 10-Year Experience in a Tertiary Hospital

Kim MH, Kim DW, Lee HS, Bang SK, Seo SH, Park KU, Oh HK, Kang SB

Purpose Universal screening for Lynch syndrome (LS) refers to routine tumor testing for microsatellite instability (MSI) among all patients with colorectal cancer (CRC). Despite its widespread adoption, real-world data on...
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Characteristics of Defecation Function Related Quality of Life According to Cancer Location in Colorectal Cancer Survivors

Oyama O, Park DH, Lee MK, Byeon Jy, Lee EB, Chung JY, Jung HJ, Park J, Kim T, Jee SH, Kim NK, Jeon JY

Purpose: The purpose of this study is to explore defecation functions related quality of life (QoL) according to the location of cancer in colorectal cancer survivors. Methods: A total of...
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Consumption of Coffee and Green Tea and the Risk of Colorectal Cancer in Korea: The Health Examinees Study

Na H, Lee J, Cho S, Shin WK, Choi JY, Kang D, Shin A

Coffee and green tea may affect colorectal physiology and contain many bioactive components, such as polyphenol and caffeine, which have antioxidant and anti-carcinogenic activities. However, the association between coffee and...
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Association between Diet-related Behaviour and Risk of Colorectal Cancer: A Scoping Review

Mohammad NMAB, Shahril MR, Shahar S, Fenech M, Sharif R

Individual dietary patterns may be influenced by diet-related behaviours, which may eventually play a significant role in contributing to colorectal cancer risk. As nearly half of colorectal cancer cases can...
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FSP-1 expression in cancer cells is relevant to long-term oncological outcomes in nonmetastatic colorectal cancer

Im SB, Cho JM, Kim HB, Shin DH, Kwon MS, Lee IY, Son GM

Purpose: Recent studies have revealed that the expression of cancer-associated fibroblast (CAF) activation biomarkers in cancer cells is associated with clinical outcomes in patients with certain types of malignant tumors....
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Correlation of long interspersed element-1 open reading frame 1 and c-Met proto-oncogene protein expression in primary and recurrent colorectal cancers

Jeon KY, Ko EJ, Chang HK, Lee SH, Ahn BK, Ock MS, Cha HJ

Background: Colorectal cancer is one of the most common cancers worldwide. Colorectal cancer that has recurred and metastasized to other organs also has a very poor prognosis. According to recent...
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Recent Progress in Immunotherapy for Metastatic Colorectal Cancer

Kim SJ, Lee J

A breakthrough in immunotherapy has changed the outlook for metastatic colorectal cancer (mCRC) treatment as the immune surveillance evasion mechanism of tumor cells has been continuously elucidated. Immune checkpoint inhibitors...
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Presepsin (soluble CD14 subtype) as a risk factor for the development of infectious and inflammatory complications in operated colorectal cancer patients

Shakeyev K, Turgunov Y, Ogizbayeva A, Avdiyenko O, Mugazov M, Grigolashvili S, Azizov I

Purpose: In this pilot study the dynamic of presepsin (soluble CD14 subtype, sCD14-ST) in blood serum was assessed as a possible risk factor for the development of systemic inflammatory response...
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A propensity score-matched analysis of advanced energy devices and conventional monopolar device for colorectal cancer surgery: comparison of clinical and oncologic outcomes

Song WJ, Bae SU, Jeong WK, Baek SK

Purpose: The safety, efficiency, and versatility of novel surgical energy devices have been proved by recent studies. This study aims to investigate the impact of surgical energy devices on operative...
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Association between serum ferritin levels and colorectal cancer risk in Korea

Kim H, Han K, Ko SH, An HJ

Background/Aims: The concentration of serum ferritin, a storage form of iron, may be associated with carcinogenesis in various cancers. There are only limited studies on the relationship between serum ferritin...
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Trends of Colorectal Cancer Screening Rates in Korea: Korean National Cancer Screening Survey 2005–2020

Park B, Lee YY, Song SY, Shin HY, Suh M, Choi KS, Jun JK

Background/Aims: Screening for colorectal cancer (CRC) is important in reducing the morbidity and mortality of CRC. Thus, this study aimed to describe the trends of CRC screening in both organized...
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Update on Diagnosis and Treatment of Colorectal Cancer

Kim CW

The rate of colorectal cancer (CRC) has altered. Early-onset CRC patients are increasing, and it is one of the main causes of cancer-related death. Based on epidemiologic change, the CRC...
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Percutaneous radiofrequency ablation of solitary hepatic metastases from colorectal cancer: risk factors of local tumor progression-free survival and overall survival

Lee HJ, Lee MW, Ahn SH, Cha DI, Ko SE, Kang TW, Song KD, Rhim H

Purpose: This study aimed to evaluate local tumor progression-free survival (LTPFS) and overall survival (OS) after percutaneous radiofrequency ablation (RFA) for solitary colorectal liver metastases (CLM)
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Unmet Needs and Quality of Life of Colorectal Cancer Survivors Immediately after Treatment Ends and 5 Years

Kim H, Wi E, Jang MH, Jo SH, Kim HK

Purpose: This study was conducted to understand the unmet needs and quality of life of colorectal cancer survivors immediately after the end of primary treatment and 5 years later. Methods:...
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Symptom Experience and Quality of Life in Colorectal Cancer Patients Undergoing Chemotherapy

Lee A, Park JH

Purpose: This study aimed to evaluate symptom experience and quality of life (QoL) and to identify the predictors of QoL among colorectal cancer patients undergoing chemotherapy. Methods: A cross-sectional study...
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Vitamin D and Colorectal Cancer: Current Perspectives and Future Directions

Na SY, Kim KB, Lim YJ, Song HJ

Vitamin D is considered to be the main mediator of the beneficial effects of sun exposure. In humans, highest expression of Vitamin D receptors is found in the intestinal tract....
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Dietary Intervention for Preventing Colorectal Cancer: A Practical Guide for Physicians

Kim SH, Moon JY, Lim YJ

Colorectal cancer (CRC) is a disease with high prevalence and mortality. Estimated preventability for CRC is approximately 50%, indicating that altering modifiable factors, including diet and body weight, can reduce...
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The Association Between Metabolic Syndrome and Colorectal Cancer Risk by Obesity Status in Korean Women: A Nationwide Cohort Study

Moon Sg, Park B

Objectives: This study aimed to determine the association between metabolic syndrome (MetS) and the incidence of colorectal cancer (CRC) in Korean women with obesity. Methods: Cancer-free women (n=6 142 486) aged...
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