- Curcumin Attenuates Acrolein-induced COX-2 Expression and Prostaglandin Production in Human Umbilical Vein Endothelial Cells
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Lee SE, Park HR, Jeon S, Han D, Park YS
- KMID: 2470810
- J Lipid Atheroscler.
- 2020 Jan;9(1):184-194.
- doi: 10.12997/jla.2020.9.1.184
OBJECTIVE: Inflammation is crucial to limiting vascular disease. Previously we reported that acrolein, a known toxin in tobacco smoke, might play an important role in the progression of atherosclerosis via... -
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- Derivation of endothelial cells from porcine induced pluripotent stem cells by optimized single layer culture system
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Wei R, Lv J, Li X, Li Y, Xu Q, Jin J, Zhang Y, Liu Z
- KMID: 2469024
- J Vet Sci.
- 2020 Jan;21(1):e9.
- doi: 10.4142/jvs.2020.21.e9
Regenerative therapy holds great promise in the development of cures of some untreatable diseases such as cardiovascular diseases, and pluripotent stem cells (PSCs) including induced PSCs (iPSCs) are the most... -
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- A Simple and Nonenzymatic Method to Isolate Human Corpus Cavernosum Endothelial Cells and Pericytes for the Study of Erectile Dysfunction
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Yin GN, Ock J, Choi MJ, Song KM, Ghatak K, Minh NN, Kwon MH, Seong DH, Jin HR, Ryu JK, Suh JK
- KMID: 2465417
- World J Mens Health.
- 2020 Jan;38(1):123-131.
- doi: 10.5534/wjmh.180091
PURPOSE: To establish a simple and nonenzymatic technique to isolate endothelial cells (ECs) and pericytes from human corpus cavernosum tissue and to evaluate the angiogenic ability of the human cavernous... -
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- Notch1 in Tumor Microvascular Endothelial Cells and Tumoral miR-34a as Prognostic Markers in Locally Advanced Triple-Negative Breast Cancer
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Kim D, Lee J, Kang J, Kim SH, Yoo TK, Oh S, Lee A
- KMID: 2470893
- J Breast Cancer.
- 2019 Dec;22(4):562-578.
- doi: 10.4048/jbc.2019.22.e56
PURPOSE: Triple-negative breast cancer (TNBC) is associated with poor prognosis with limited treatment options. Angiogenesis is known to be involved in the progression of TNBC, and targeting this pathway results... -
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- Docosahexaenoic acid reduces adenosine triphosphate-induced calcium influx via inhibition of store-operated calcium channels and enhances baseline endothelial nitric oxide synthase phosphorylation in human endothelial cells
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Vu TT, Dieterich , Vu TT, Deussen A
- KMID: 2455811
- Korean J Physiol Pharmacol.
- 2019 Sep;23(5):345-356.
- doi: 10.4196/kjpp.2019.23.5.345
Docosahexaenoic acid (DHA), an omega-3-fatty acid, modulates multiple cellular functions. In this study, we addressed the effects of DHA on human umbilical vein endothelial cell calcium transient and endothelial nitric... -
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- C3a Receptor Inhibition Protects Brain Endothelial Cells Against Oxygen-glucose Deprivation/Reperfusion
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Ahmad S, Kindelin A, Khan SA, Ahmed M, Hoda MN, Bhatia K, Ducruet AF
- KMID: 2450214
- Exp Neurobiol.
- 2019 Apr;28(2):216-228.
- doi: 10.5607/en.2019.28.2.216
The complement cascade is a central component of innate immunity which plays a critical role in brain inflammation. Complement C3a receptor (C3aR) is a key mediator of post-ischemic cerebral injury,... -
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- MiR-590 Inhibits Endothelial Cell Apoptosis by Inactivating the TLR4/NF-κB Pathway in Atherosclerosis
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Yang L, Gao C
- KMID: 2441308
- Yonsei Med J.
- 2019 Mar;60(3):298-307.
- doi: 10.3349/ymj.2019.60.3.298
PURPOSE: Previous study has well documented the anti-apoptotic effects of miR-590 on oxidized low-density lipoprotein (ox-LDL)-treated endothelial cells (ECs). However, the mechanism underlying the anti-apoptotic effects of miR-590 in ox-LDL-treated... -
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- Autophagy Is a Potential Target for Enhancing the Anti-Angiogenic Effect of Mebendazole in Endothelial Cells
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Sung SJ, Kim HK, Hong YK, Joe YA
- KMID: 2432075
- Biomol Ther.
- 2019 Jan;27(1):117-125.
- doi: 10.4062/biomolther.2018.222
Mebendazole (MBZ), a microtubule depolymerizing drug commonly used for the treatment of helminthic infections, has recently been noted as a repositioning candidate for angiogenesis inhibition and cancer therapy. However, the... -
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- Differentiation of CD31-Positive Vascular Endothelial Cells from Organoid Culture of Dental Pulp Stem Cells
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Seo EJ, Park JK, Jeong H, Kang JS, Kim HR, Jang IH
- KMID: 2437358
- Int J Oral Biol.
- 2018 Jun;43(2):77-82.
- doi: 10.11620/IJOB.2018.43.2.077
The mesenchymal stem cells (MSCs) that reside in dental tissues hold a great potential for future applications in regenerative dentistry. In this study, we used human dental pulp cells, isolated... -
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- Xenotransplantation of Cultured Human Corneal Endothelial Cell Sheets
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Lee YP, Chung TY, Hyon JY, Shin YJ
- KMID: 2413811
- J Korean Ophthalmol Soc.
- 2018 Jun;59(6):497-504.
- doi: 10.3341/jkos.2018.59.6.497
PURPOSE: To investigate the possibility of transplantation into rabbits of collagenase-induced cultured human corneal endothelial cell plate-rabbit corneal stromal complexes. METHODS: Human corneal endothelial cells were isolated from residual corneal limbus... -
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- In vitro treatment of lipopolysaccharide increases invasion of Pasteurella multocida serotype B:2 into bovine aortic endothelial cells
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Yap SK, Zakaria Z, Othman SS, Omar AR
- KMID: 2407620
- J Vet Sci.
- 2018 Mar;19(2):207-215.
- doi: 10.4142/jvs.2018.19.2.207
Pasteurella multocida serotype B:2 causes hemorrhagic septicemia in cattle and buffalo. The invasion mechanism of the bacterium when invading the bloodstream is unclear. This study aimed to characterize the effects... -
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- Relationship between Pericytes and Endothelial Cells in Retinal Neovascularization: A Histological and Immunofluorescent Study of Retinal Angiogenesis
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Choi SH, Chung M, Park SW, Jeon NL, Kim JH, Yu YS
- KMID: 2402723
- Korean J Ophthalmol.
- 2018 Feb;32(1):70-76.
- doi: 10.3341/kjo.2016.0115
PURPOSE: To evaluate the relationship between pericytes and endothelial cells in retinal neovascularization through histological and immunofluorescent studies. METHODS: C57BL/6J mice were exposed to hyperoxia from postnatal day (P) 7 to... -
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- Protective Effect of Allium tuberosum Extract on Vascular Inflammation in Tumor Necrosis Factor-α-induced Human Vascular Endothelial Cells
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Hur HJ, Lee AS
- KMID: 2434284
- J Cancer Prev.
- 2017 Dec;22(4):228-233.
- doi: 10.15430/JCP.2017.22.4.228
BACKGROUND: Endothelial adhesion molecule expression induced by pro-inflammatory cytokine plays an important role in vascular endothelial cell injury, leading to vascular disease. Allium tuberosum (AT), which is used as a... -
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- Myricetin Inhibits Angiogenesis by Inducing Apoptosis and Suppressing PI3K/Akt/mTOR Signaling in Endothelial Cells
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Kim GD
- KMID: 2434283
- J Cancer Prev.
- 2017 Dec;22(4):219-227.
- doi: 10.15430/JCP.2017.22.4.219
BACKGROUND: Myricetin has been shown to possess potential antiangiogenic effects in endothelial cells. However, the underlying mechanisms are not fully understood. Therefore, we evaluated its antiangiogenic effects in human umbilical... -
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- Active maintenance of endothelial cells prevents kidney fibrosis
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Yang SH, Kim YC, An JN, Kim JH, Lee J, Lee HY, Cho JY, Paik JH, Oh YK, Lim CS, Kim YS, Lee JP
- KMID: 2405108
- Kidney Res Clin Pract.
- 2017 Dec;36(4):329-341.
- doi: 10.23876/j.krcp.2017.36.4.329
BACKGROUND: Soluble epoxide hydrolase (sEH) expressed by endothelial cells catalyzes the metabolism of epoxyeicosatrienoic acids (EETs), which are vasoactive agents. METHODS: We used a unilateral ureteral obstruction mouse model of kidney... -
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- Hepatogenic Differentiation Capacity of Human Wharton’s Jelly Mesenchymal Stem Cell in a Co-culturing System with Endothelial Cells in Matrigel/collagen Scaffold in the Presence of Fetal Liver Extract
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Khodabandeh Z, Vojdani Z, Talaei-Khozani T, Bahmanpour S
- KMID: 2400875
- Int J Stem Cells.
- 2017 Nov;10(2):218-226.
- doi: 10.15283/ijsc17003
BACKGROUND: Human Wharton’s jelly mesenchymal stem cells (HWJMSCs) isolated from medical waste product can be considered as an accessible source of cells in regenerative medicine. Stem cell-derived hepatocytes have poor... -
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- Tanshinone IIA Protects Endothelial Cells from Hâ‚‚Oâ‚‚-Induced Injuries via PXR Activation
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Zhu H, Chen Z, Ma Z, Tan H, Xiao C, Tang X, Zhang B, Wang Y, Gao Y
- KMID: 2395809
- Biomol Ther.
- 2017 Nov;25(6):599-608.
- doi: 10.4062/biomolther.2016.179
Tanshinone IIA (Tan IIA) is a pharmacologically active substance extracted from the rhizome of Salvia miltiorrhiza Bunge (also known as the Chinese herb Danshen), and is widely used to treat... -
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- Biological Interaction Between Human Gingival Fibroblasts and Vascular Endothelial Cells for Angiogenesis: A Co-culture Perspective
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Allah NU, Berahim Z, Ahmad A, Kannan TP
- KMID: 2394984
- Tissue Eng Regen Med.
- 2017 Oct;14(5):495-505.
- doi: 10.1007/s13770-017-0065-y
Advancement in cell culture protocols, multidisciplinary research approach, and the need of clinical implication to reconstruct damaged or diseased tissues has led to the establishment of three-dimensional (3D) test systems... -
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- A calpain inhibitor protects against fractalkine production in lipopolysaccharide-treated endothelial cells
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Jang J, Yoon Y, Oh DJ
- KMID: 2416091
- Kidney Res Clin Pract.
- 2017 Sep;36(3):224-231.
- doi: 10.23876/j.krcp.2017.36.3.224
BACKGROUND: Fractalkine (CX3CL1) is a chemokine with a unique CX3C motif and is produced by endothelial cells stimulated with lipopolysaccharide (LPS), tumor necrosis factor (TNF)-α, interleukin (IL)-1, and interferon-γ. There... -
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- Co-culture of Human Dental Pulp Stem Cells and Endothelial Cells Using Porous Biopolymer Microcarriers: A Feasibility Study for Bone Tissue Engineering
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Jin GZ, Kim HW
- KMID: 2394973
- Tissue Eng Regen Med.
- 2017 Aug;14(4):393-401.
- doi: 10.1007/s13770-017-0061-2
Delivery of stem cells with osteogenesis while enabling angiogenesis is important for vascularized bone tissue engineering. Here a three-dimensional (3D) co-culture system of dental pulp stem cells (DPSCs) and endothelial... -
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