Korean J Infect Dis.
2001 Dec;33(6):448-452.
Human Herpes Virus-6 Meningoencephalitis Following Allogeneic Hematopoietic Stem Cell Transplantation
- Affiliations
-
- 1Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. fire@cmc.cuk.ac.kr
- 2Department of Clinical Research Institute of St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Abstract
- Two cases of human herpesvirus-6 (HHV-6) encephalitis that occurred after allogeneic hematopoietic stem cell transplant (HSCT) are presented. Both patients reported fever, skin rashes, and neurological symptoms, characterized by disorientation, confusion and drowsy mental status. HHV-6B DNA was detected from the cerebrospinal fluid (CSF) specimens by a multiplex polymerase chain reaction (PCR) assay including EBV, CMV, HHV-6B. After treatment with intravenous gan ciclovir for 2~3 weeks, all clinical manifestations were resolved and the HHV-6B DNA was cleared from the CSF in both patients. HHV-6 should be considered as a possible cause of neurological symptoms after HSCT, and prompt antiviral treatment should be begun.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Two Cases of Hodgkin's Lymphoma after Allogeneic Hematopoietic Cell Transplantation
- A case of pneumomediastinum combined with chronic graft-versus-host disease following allogeneic hematopoietic stem cell transplantation
- Common Infectious Diseases in Hematopoietic Stem Cell Transplant Recipients
- Comparison of Quality of Life of Autologous and Allogeneic Hematopoietic Stem Cell Transplantation Recipients
- Allogeneic hematopoietic stem cell transplantation for myelodysplastic syndromes
