Korean J Nucl Med.  1999 Dec;33(6):537-542.

A Case of Zollinger-Ellison Syndrome with Gastrinoma Localized by 111In-Pentetreotide Scan

• Jeong HJ
• Ryu JS
• Kim JS
• Moon DH
• Jung HY
• Ha HK
• Lee HK

Abstract

In patient with Zollinger-Ellison syndrome, it is difficult to localize gastrinoma because the tumor is frequently small and multiple. However, accurate localization of the tumor is important for the treatment. Among various imaging modalities, somatostatin receptor scintigraphy (SRS) has been recognized to be the most sensitive tool for the detection of neuroendocrine tumors such as gastrinomas based on the presence of high-affinity binding sites for somatostatin. Recently, we experienced a case of Zollinger-Ellison syndrome caused by gastrinomas which was localized by SRS. This is the first case report of gastrinoma detected by SRS in Korea. SRS can facilitate tumor detection in patient with Zollinger-Ellison syndrome and should be considered as the first-line diagnostic method in the early course of the disease.

Keyword

Somatostatin receptor scintigraphy; Gastrinoma; Zollinger-Ellison syndrome

MeSH Terms

Binding Sites
Gastrinoma*
Humans
Korea
Neuroendocrine Tumors
Radionuclide Imaging
Receptors, Somatostatin
Somatostatin
Zollinger-Ellison Syndrome*
Receptors, Somatostatin
Somatostatin