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Nuclear Factors Bind to the Specific Sites in Promoter Region of Human YB-1 Gene

Kim YR, Han SW, Ryu PY, Kim KK, Ahn BW, Shin BA

  • KMID: 2172429
  • Chonnam Med J.
  • 2001 Mar;37(1):7-12.
This study was designed to identify the presence of the nuclear factors binding to promoter region of human YB-1 gene and determine their specific binding sites. Nuclear extracts were prepared...
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The effect of carbon monoxide on the [3H] 5-hydroxytryptamine binding sites in neonatal rats

Kim YS, Jeong BY, Cho SH

  • KMID: 1691964
  • J Korean Neuropsychiatr Assoc.
  • 1991 Jul;30(4):652-659.
No abstract available.
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Gonadotropin hormone binding sites in human ovarian neoplasms

Kim JW, Chang YK, Park KH, Kim DK, Kwak HM, Oh KS, Song CH

  • KMID: 2259679
  • Korean J Obstet Gynecol.
  • 1993 Jul;36(7):2489-2496.
No abstract available.
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Prediction of Metal Ion Binding Sites in Proteins from Amino Acid Sequences by Using Simplified Amino Acid Alphabets and Random Forest Model

Kumar S

Metal binding proteins or metallo-proteins are important for the stability of the protein and also serve as co-factors in various functions like controlling metabolism, regulating signal transport, and metal homeostasis....
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Studies on the Specific Estradiol Binding Site on Rat Uterine Membranes

Yoon MC, Ryu KZ

  • KMID: 2461661
  • J Korean Soc Endocrinol.
  • 1996 Dec;11(4):510-516.
Backgroand: In our previous study, it was demonstrated that estradiol-dependent prostaglandin synthesis may be mediated by cAMP elevation during the process of iplantation in rats. The present study was undertaken...
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IL-18Ralpha Mediated GATA-3 Induction by Th2 Cells: IL-12 Supports IL-18Ralpha Expression in Th2 Cells

Joo IS, Sun MJ, Kim DY, Lee SJ, Ha YM, Cho JJ, Park CS, Ahn HJ

BACKGROUND: IL-18 was originally cloned as a IFN-gamma inducing factor in primed T cells. In synergy with IL-12, IL-18 has been shown to induce strikingly high levels of IFN-gamma production...
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The Characterization of CpG Methylation of ERalpha and ERbeta Gene in the Breast Cancer

Kim SJ, Kim TW, Lee SY, Park SJ, Lee ES, Kang HS

PURPOSE: Aberrant methylation of promoter cytosine guanine dinucleotide (CpG) islands is known to be responsible for the alteration and silencing of cancer genes. The data presented here show that most...
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(3H)Ryanodine binding sites of SR vesicles of the chicken pectoral muscle

Yun HY, Jeon JR, Hong JH, Hur GM, Lee JH, Seok JH

  • KMID: 2071509
  • Korean J Physiol Pharmacol.
  • 1997 Aug;1(4):377-384.
To investigate the properties of ryanodine binding sites of the bird skeletal SR vesicles, SDS PAGE, purification of RyR, and (3H)ryanodine binding study were carried out in the SR vesicles prepared from...
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Changes of AP-1 Binding Activities in Rat Brain by Electroconvulsive Shock

Joo YH, Ahn YM, Kang UG, Koo YJ, Kim YS

  • KMID: 2340872
  • J Korean Neuropsychiatr Assoc.
  • 2003 Sep;42(5):544-552.
OBJECTIVES: ECS could have therapeutic effects on psychiatric illnesses by inducing IEGs, which in turn regulates expression of their target genes. We observed AP-1 binding activity and identified AP-1 binding...
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Problems Associated with I-125 Oxytocin Binding to Membrane Receptors

Kim IK, Choi JO, Kang DH

Radioiodinated oxytocin prepared by the lactoperoxidase method exhibited a substantial biologic activity in uterotonic assay of the rat uterus. 125I-oxytocin was bound to the uterine membrane particulate fraction, but the...
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Ontogeny of Adrenergic Receptors in the Rat Amygdala

Chung YY, Bae CS

  • KMID: 1530112
  • Korean J Anat.
  • 1998 Jun;31(3):447-463.
The mammalian amygdala comprises a heterogeneous complex of cytoarchitectonically, histochemically and connectionally distinct nuclei. To investigate the developmental changes and regional distributions of adrenoceptor binding sites in the adult and...
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Histochemical Characterization of the Lectin-binding Sites in the Equine Vomeronasal Organ

Lee JY, Kang TY, Lee YD, Shin TK

  • KMID: 1099816
  • J Vet Sci.
  • 2003 Apr;4(1):15-19.
The binding specificities of various lectins, such as the Dolichos biflorus agglutinin (DBA), soybean agglutinin (SBA), and the Bandeiraea simplicifolia BS-1 (Isolectin B4), Triticum vulgaris (WGA), Arachis hypogaea (PNA), and...
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Enrichment of rare alleles within epigenetic chromatin marks in the first intron

Jo SS, Choi SS

In previous studies, we demonstrated that some sites in the first intron likely regulate gene expression. In the present work, we sought to further confirm the functional relevance of first...
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Prediction of Mammalian MicroRNA Targets : Comparative Genomics Approach with Longer 3' UTR Databases

Nam S, Kim YK, Kim P, Kim VN, Shin S, Lee S

  • KMID: 1572671
  • Genomics Inform.
  • 2005 Sep;3(3):53-62.
MicroRNAs play an important role in regulating gene expression, but their target identification is a difficult task due to their short length and imperfect complementarity. Burge and coworkers developed a...
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C/EBP binding activity to site F of the rat GLUT2 glucose transporter gene promoter is attenuated by c-Jun in vitro

Kim JW, Ahn YH

  • KMID: 755211
  • Exp Mol Med.
  • 2002 Nov;34(5):379-384.
The expression of the GLUT2 glucose transporter gene in liver is suppressed in cultured hepatoma cell lines and primary cultured hepatocytes. Earlier report showed that CCAAT/enhancer binding protein (C/EBP) regulates...
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Impact of Nucleotide Mutations at the HNF3- and HNF4-Binding Sites in Enhancer 1 on Viral Replication in Patients with Chronic Hepatitis B Virus Infection

Cho EY, Kim HJ, Park C, So HS, Park RK, Kim HC

  • KMID: 1806674
  • Gut Liver.
  • 2013 Sep;7(5):569-575.
BACKGROUND/AIMS: The hepatitis B virus (HBV) genome contains binding sites for hepatocyte nuclear factors (HNF) 3 and 4 in the core domain of enhancer 1 (Enh1), and mutations in this...
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Classic Studies on the Interaction of Cocaine and the Dopamine Transporter

Verma V

The dopamine transporter is responsible for recycling dopamine after release. Inhibitors of the dopamine transporter, such as cocaine, will stop the reuptake of dopamine and allow it to stay extracellularly,...
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In Silico Structural and Functional Annotation of Hypothetical Proteins of Vibrio cholerae O139

Islam MS, Shahik SM, Sohel M, Patwary NI, Hasan MA

In developing countries threat of cholera is a significant health concern whenever water purification and sewage disposal systems are inadequate. Vibrio cholerae is one of the responsible bacteria involved in...
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Immunoelectron-microscopic localization of IgE binding site of mugwort pollen

Park HS, Kim JW, Hong CS

To elucidate the IgE binding site of mugwort (Artemisia vulgaris r.) pollen, pollen grains were frozen and fixed using a cryocut. They were incubated with antibodies according to the following...
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Regulation of mammalian pyruvate dehydrogenase complex by phosphorylation: complexity of multiple phosphorylation sites and kinases

Patel MS, Korotchkina LG

  • KMID: 1457529
  • Exp Mol Med.
  • 2001 Dec;33(4):191-197.
This review summarizes the recent developments on the regulation of human pyruvate dehydrogenase complex (PDC) by site-specific phosphorylation by four kinases. Mutagenic analysis of the three phosphorylation sites of human...
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