Korean J Occup Environ Med.  2002 Sep;14(3):326-333.

A Case of Reactive Dye Induced Asthma in an Exposed Worker near a Dye Factory

Affiliations
  • 1Industrial Safety and Health Research Institute, KOSHA, Korea. kobawoo@kosha.net
  • 2Department of Internal Medicine, Yonsei University College of Medicine, Korea.

Abstract


OBJECTIVES
Reactive dye (RD) induced bronchial asthma is a well known form of occupational asthma. We report a case of occupational asthma due to RD in an exposed worker near a dye factory.
METHODS
To evaluate the work-relatedness of bronchial asthma, we examined all possibilities by considering the working environment and performing a personal clinical survey, such as interview on the previous history of allergic diseases, clinical and immunological investigation including skin prick tests, bronchoprovocation tests, and serial peak expiratory flow rates (PEFR).
RESULTS
Occupational asthma of internal origin was excluded by the characteristics of asthma, absence of occupational allergens, and negative PEFR result in the worker's own workplace. However, specific IgE and skin prick tests with reactive dye allergens were all strongly positive. RD challenge test showed maximal 34 % fall of FEV1 at 10 minutes of exposure (PD2 0: 2.11 mg/ml).
CONCLUSIONS
We concluded that this case was an example of bronchial asthma by external occupational allergens. This case suggests that RD induced asthma may also occur in workers and inhabitants who have lived near a reactive dye manufacturing factory.

Keyword

Occupational asthma; Reactive dye
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