Korean J Occup Environ Med.  1998 May;10(2):282-289.

Sister-Chromatid Exchanges in Lymphocytes of Medical Students Exposed to Formaldehyde

Affiliations
  • 1Department of Occupational medicine, Hanyang University Hospital, Korea.
  • 2Department of Medical Genetics, College of Medicine, Hanyang University, Korea.
  • 3Department of Anatomy, College of medicine, Hanyang University, Korea.
  • 4Koryo Industrial Medical Center, Young Nam Medical Foundation, Korea.

Abstract

Sister-chromatic exchanges measured in the peripheral lymphocytes of 15 non-smoking medical students after exposure to formaldehyde during a 24-week anatomy class showed a small but significant (p=0.0468) increase when compared with samples obtained from the same individuals immediately before exposure. Mean frequencies of sister-chromatic exchange of cultured peripheral lymphocytes were 5.40+/-0.24 from the samples before exposure and 5.87+/-0.22 from the same samples after exposure. Breathing-zone air samples collected by formaldehyde monitoring kit with digital colorimeter (SKC) showed a mean concentration of 0.72+/-0.02 ppm formaldehyde.

Keyword

Sister-chromatid exchange (SCE); Formaldehyde; Mutagenicity

MeSH Terms

Formaldehyde*
Humans
Lymphocytes*
Students, Medical*
Formaldehyde
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