Chonnam Med J.
2006 Apr;42(1):49-52.
A Case of Primary Hyperparathyroidism with Osteitis Fibrosa Cystica Simulating as Bone Tumor
- Affiliations
-
- 1Department of Internal Medicine, Chonnam National University Medical School, Chonnam National University Research Institute of Medical Science, Gwangju, Korea. jdjcjr@chol.com
Abstract
- Primary hyperparathyroidism was previously characterized by severe hypercalcemia, recurrent nephrolithiasis, osteoporosis and osteitis fibrosa cystica. But recently, it became increasingly rare to find typical findings due to early detection of hypercalcemia. Occasionally, osteitis fibrosa cystica can be mistaken for a malignant lesion. Radiologically, the multiple, osteolytic lesions may be indistinguishable from metastatic disease. In this report we describe a young woman with severe hyperparathyroidism and bony lesions. Magnetic resonance image showed a 1.5-cm-sized mass-like lesion in the proximal tibial metaphysis. Bone biopsy was done and the findings was compatible with osteitis cystica fibrosa. Serum calcium level was 12 mg/dl and the intact parathyroid hormone level was 1,591 pg/ml. Neck ultrasonography and Tc99m-sestamibi scan revealed a parathyroid mass. A surgical excision of the parathyroid tumor was performed and confirmed as a parathyroid adenoma by pathology. Although rare, hyperparathyroidism should be considered in patients with multiple osteolytic lesions.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Fulminant primary hyperparathyroidism in a child with early menifestation of extensive osteitis fibrosa cystica: A case report
- A Case of Parathyroid Carcinoma Presenting as Brown Tumors
- Brown Tumor of the Cervical Spines: A Case Report with Literature Review
- A Clinical Study on 3 Unusual Cases of Generalized Osteitis Fibrosa Cystica Associated with Parathyroid Adenoma Developed in Young Age
- A Case of Primary Hyperparathyroidism with Rapid Regression of a Brown Tumor after Parathyroidectomy
