Ann Dermatol.  2016 Oct;28(5):660-662. 10.5021/ad.2016.28.5.660.

A Case of Linear IgA Bullous Dermatosis Associated with Systemic Lupus Erythematosus

• Lee HJ
• Yun SJ
• Lee SC
• Lee JB

• KMID: 2382901
• DOI: http://doi.org/10.5021/ad.2016.28.5.660

Abstract

No abstract available.

MeSH Terms

Linear IgA Bullous Dermatosis*
Lupus Erythematosus, Systemic*

Figure

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  Fig. 1 Generalized erythematous vesicles and erosive patches arising on (A) chest and (B) back in a 33-year-old patient who developed linear IgA bullous dermatosis and systemic lupus erythematosus.

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  Fig. 2 (A) Histopathologic findings showing subepidermal blister and infiltration of lymphocytes and neutrophils in the upper dermis (H&E, ×200). (B) Indirect IF with 1 M NaCl split-skin showed linear depositions of immunoglobulin (Ig) A and IgG in the roof of separated skin (a: IgA, b: IgG). (C) Immunoblotting using normal human foreskin epidermal extracts showed 120 kDa, 230 kDa molecular weight bands on both IgA, IgG, respectively. MM: molecular weight marker, BP: bullous pemphigoid, PV: pemphigus vulgaris, PF: pemphigus foliaceus.

Reference

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