Korean J Gastroenterol.  2014 Oct;64(4):239-245. 10.4166/kjg.2014.64.4.239.

Two Cases of Hepatic Sinusoidal Dilatation Mimicking Hepatic Metastases

  • 1Jeju National University School of Medicine, Jeju, Korea.
  • 2Department of Internal Medicine, Jeju National University Hospital, Jeju, Korea. choyk1120@hanmail.net
  • 3Department of Pathology, Jeju National University Hospital, Jeju, Korea.
  • 4Department of Radiology, Jeju National University Hospital, Jeju, Korea.


Hepatic sinusoidal dilatation is a rare benign vascular disorder characterized by focal dilatation of the sinusoidal spaces. In most cases, the underlying etiology is unclear but it may be related to the impairment of venous outflow or sinusoidal infiltration by diverse causes. Diagnosing hepatic sinusoidal dilatation based soley on imaging study is not easy since there are no pathognomonic radiologic findings indicative of this condition. Recently, the authors experience two cases of hepatic sinusoidal infiltration. The first patient was a 53-year-old man detected to have multiple hepatic nodules on ultrasonography (US) during a routine medical check-up. The second patient was an 82-year-old woman with abdominal discomfort who was referred from local clinic with high suspicion of hepatic metastases on US. In both cases, CT scan demonstrated multiple nodules with rim enhancement on arterial phase that became iso-dense to adjacent liver parenchyma on delayed phase. On MRI, these nodules showed rim enhancement on arterial phase, had high signal intensity on T2 weighted images, and became iso-intense with partial defect on hepatobiliary phase. Because imaging studies could not exclude the presence of hepatic metastases, liver biopsy was performed and it demonstrated hepatic sinusoidal dilatation with well preserved reticulin fiber without any evidence of malignancy. Herein, we report two cases of idiopathic hepatic sinusoidal dilatation mimicking hepatic metastases.


Hepatic sinusoidal dilatation; Hepatic metastases
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