Intest Res.  2010 Jun;8(1):24-29. 10.5217/ir.2010.8.1.24.

Comparison of Bowel Preparation Depending on Completion Time of Polyethylene Glycol Ingestion and Start Time of Colonoscopy

Affiliations
  • 1Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University College of Medicine, Seoul, Korea. diksmc.park@samsung.com
  • 2Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea.
  • 3Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea.
  • 4Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea.
  • 5Department of Internal Medicine, Samsung Seoul Hospital, Sungkyunkwan University College of Medicine, Seoul, Korea.
  • 6Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
  • 7Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
  • 8Department of Internal Medicine, Koshin University College of Medicine, Busan, Korea.
  • 9Department of Internal Medicine, Hallym University College of Medicine, Seoul, Korea.
  • 10Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea.
  • 11Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.

Abstract

BACKGROUND/AIMS
Polyethylene glycol (PEG) solution is the most widely used bowel preparation agent for colonoscopy because of its safety and efficacy in colon cleansing. It has been hypothesized that the timing of colon preparation may influence the quality of colon cleansing, and therefore affect the diagnostic yield of colonoscopy. The aim of this study was to determine the optimal interval of time between complete ingestion of PEG and performing colonoscopy.
METHODS
We prospectively enrolled 1,355 patients who had undergone a PEG-based bowel preparation on the day of colonoscopy in 11 tertiary hospitals in Korea between March 2008 and February 2009. All colonoscopies were performed in the afternoon. The start time of PEG ingestion, completion time of PEG ingestion, dose of PEG ingested, start time of colonoscopy, and the quality of bowel cleansing were recorded.
RESULTS
There was no difference of cleansing quality of bowel preparation between three groups of less than 7 hours of elapsed time (2< or = and <3 hours, 3< or = and <5 hours, 5< or = and <7 hours). However, group of more than 7 hours of elapsed time presented poor cleansing quality than others (P<0.01).
CONCLUSIONS
If>7 hours elapses after ingestion of PEG, the quality of bowel preparation is poor. Therefore, depending on the time colonoscopy is scheduled, the start time of PEG ingestion may need to be adjusted.

Keyword

Colonoscopy; Polyethylene Glycol (PEG) Solution; Bowel Preparation

MeSH Terms

Colon
Colonoscopy
Eating
Humans
Korea
Polyethylene
Polyethylene Glycols
Prospective Studies
Tertiary Care Centers
Polyethylene
Polyethylene Glycols
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