J Korean Ophthalmol Soc.  2000 Aug;41(8):1801-1806.

A Case of Human Amniotic Membrane Transplantation for the Treatment of Overhanging Bleb

• Kim S
• Kee C

Abstract

Overhanging bleb after trabeculectomy is a late complication which can cause visual disturbance, ocular pain and even be a risk factor of late endophthalmitis. When it fails to be managed with conservative and less invasive treatment, the bleb is to be excised surgically. In this case, the shortage of conjunctiva in the course of partial excision of the bleb was successfully managed by human amniotic membrane transplantation. Amniotic membrane is avascular tissue with thick basement membrane and rich stroma, and it can supply the conjunctiva with basement membrane and growth factors. We report the usefulness of amniotic membrane transplantation as a temporary substitute of conjunctiva and a source of stroma for its growth in the excision of overhanging bleb.

Keyword

Amniotic membrane transplantation; Overhanging bleb; Trabeculectomy

MeSH Terms

Amnion*
Basement Membrane
Blister*
Conjunctiva
Endophthalmitis
Humans*
Intercellular Signaling Peptides and Proteins
Risk Factors
Trabeculectomy
Intercellular Signaling Peptides and Proteins