Korean J Anesthesiol.  1996 Jun;30(6):663-667. 10.4097/kjae.1996.30.6.663.

The Effect of 10 % Lidocaine Spray on Hemodynamics and Postoperative Sore Throat Accompanied by Endotracheal Intubation

• Oh YJ
• Kim HK
• Park DH

• KMID: 1934795
• DOI: http://doi.org/10.4097/kjae.1996.30.6.663

Abstract

BACKGROUND: Laryngoscopy and endotracheal intubation are potential stimuli that can frequently induce increased sympathetic activity and postoperative sore throat. The authors studied the effects of 10% lidocaine (Xylocaine 10% Spray, Astra, Sweden) spray on hemodynamic responses and postoperative sore throat after laryngoscopy and endotracheal intubation.
METHODS
Forty ASA 1 patients undergoing elective surgery were allocated randomly to two groups. Control group was intubated without 10% lidocaine spray. Study group was intubated with 10% lidocaine spray to pharyngolaryngeal(1 mg/kg) and intratracheal (l mg/kg) sites during the induction of anesthesia.
RESULTS
The results obtained were as follows. Compared with the control group, systolic blood pressure, diastolic blood pressure and mean arterial blood pressure were significantly decreased in 10% lidocaine spray group. But the incidence of arrhythmia and an increase in heart rate were not different between two groups. Sore throat was more significantly less in 10% lidocaine spray group than the control group.
CONCLUSIONS
The elevation of blood pressure, and the incidence of postoperative sore throat accompanied by endotracheal intubation can be prevented with 10% lidocaine spray to pharyngolaryngeal and intratracheal sites before intubation.

Keyword

Anesthetics; local; lidocaine; Intubation

MeSH Terms

Anesthesia
Anesthetics
Arrhythmias, Cardiac
Arterial Pressure
Blood Pressure
Heart Rate
Hemodynamics*
Humans
Incidence
Intubation
Intubation, Intratracheal*
Laryngoscopy
Lidocaine*
Pharyngitis*
Anesthetics
Lidocaine