Korean J Gastrointest Endosc.  1999 Dec;19(6):983-989.

A Case of a Solid and Papillary Epithelial Neoplasm of the Pancreas with Local Invasion into the Duodenum

• Kim HJ
• Lee S
• Choi SI
• Park SH
• Kim SK
• Yang SW
• Seo JP
• Park HB
• Park YK
• Jung JJ

Abstract

A solid and papillary epithelial neoplasm of the pancreas is a very rare and low-grade type of malignancy, although an increasing number of cases have been reported in recent years. Patients with a solid and papillary epithelial neoplasm of the pancreas have a good prognosis and may be cured if the disease is diagnosed before metastasis and diffuse local invasion. A 23-year-old female who had a 4-year history of recurrent abdominal pain, was admitted due to lower abdominal pain. Incidentally a calcified, 6 4 cm sized ovoid mass was found in the right upper quadrant, from a simple abdominal X-ray. An ERCP, abdominal sonography, and CT were performed, as well as a pylorus preserving pancreatoduodenectomy. Gross pathologic examination revealed a well encapsulated mass with cystic degeneration and hemorrhagic necrosis. Microscopically, the tumor had papillary fronds with a fibrovascular connective tissue core. There was focal infiltration of tumor cells into the duodenal wall and heterotropic pancreatic tissue in the submucosa. Immunohistochemistry revealed positivity for neuron-specific enolase. The patient maintained a healthy status for one year since the operation.

Keyword

Solid and papillary epithelial neoplasm of the pancreas

MeSH Terms

Abdominal Pain
Cholangiopancreatography, Endoscopic Retrograde
Connective Tissue
Duodenum*
Female
Humans
Immunohistochemistry
Necrosis
Neoplasm Metastasis
Neoplasms, Glandular and Epithelial*
Pancreas*
Pancreaticoduodenectomy
Phosphopyruvate Hydratase
Prognosis
Pylorus
Young Adult
Phosphopyruvate Hydratase