Korean J Med.  2004 Nov;67(Suppl 3):S857-S861.

A case of benign metastasizing leiomyoma in the lung of woman with a history of myomectomy

Affiliations
  • 1Department of Internal Medicine, National Medical Center, Seoul, Korea. suyeoni@yahoo.co.kr
  • 2Department of Radiology, National Medical Center, Seoul, Korea.
  • 3Department of Chest surgery, National Medical Center, Seoul, Korea.
  • 4Department of Internal Medicine, Green Hospital, Seoul, Korea.
  • 5Department of Anatomical Pathology, National Cancer Center, Seoul, Korea.

Abstract

Benign metastasizing leiomyoma is usually detected years after hysterectomy or myomectomy and characterized by well-circumscribed, singular or, often, multiple nodules. The patient was a 33-year-old woman who presented with cough. She underwent a myomectomy for a large uterine leiomyoma 9 years ago. And now she has recurrent uterine myoma. Multiple nodular lesions in both whole lung fields were incidentally found on a routine chest radiograph. Video-assisted thoracoscopy (VATs) was performed. The resected small nodular lesions composed of extremely well- defferentiated smooth muscle cells with collagen. On immunohistochemical stain, they are positive for smooth muscle markers (desmin and actin). There is no definite evidence of malignancy. Therefore, these multiple nodules are considered as benign metastasizing leiomyoma from a uterine leiomyoma. We report this case with review of literatures.

Keyword

Lung neoplasm; Uterine leiomyoma; Bilateral multiple nodules; Hormonal therapy

MeSH Terms

Adult
Collagen
Cough
Female
Humans
Hysterectomy
Leiomyoma*
Lung Neoplasms
Lung*
Muscle, Smooth
Myocytes, Smooth Muscle
Radiography, Thoracic
Thoracoscopy
Collagen
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