Korean J Dermatol.  1990 Dec;28(6):702-707.

Detection of Human Papillomavirus DNA by In Situ Hybridization Using Biotinylated DNA Probes in Codylomata Acuminata

Abstract

Human Papillomaviruses(HPVs) are regarded as sexually transmitable and closely associated with precancerous lesions or invasive cancers of the vulva, vagina, and cer V1X. In situ hybridization, besides showing higher sensitivity, allowed the identification of specific viral types. We studied 12 cases of condylomata accuminata for HPV typing by in situ hybridization techenique. Ten cases(83.3 % ) showed positive for HPV type 6/11, and 2 cases(16.7% ) were positive for HPV type 16/18.

Keyword

Condylomata accuminata; HPV; In situ hyb; Idization

MeSH Terms

DNA Probes*
DNA*
Humans*
In Situ Hybridization*
Vagina
Vulva
DNA
DNA Probes
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